Search

Your search keyword '"Wiederhold, N P"' showing total 7 results
Start Over Author "Wiederhold, N P" Publisher american society for microbiology
7 results on '"Wiederhold, N P"'

1. International Evaluation of MIC Distributions and Epidemiological Cutoff Value (ECV) Definitions for Fusarium Species Identified by Molecular Methods for the CLSI Broth Microdilution Method

Author

Espinel-Ingroff, A., primary, Colombo, A. L., additional, Cordoba, S., additional, Dufresne, P. J., additional, Fuller, J., additional, Ghannoum, M., additional, Gonzalez, G. M., additional, Guarro, J., additional, Kidd, S. E., additional, Meis, J. F., additional, Melhem, T. M. S. C., additional, Pelaez, T., additional, Pfaller, M. A., additional, Szeszs, M. W., additional, Takahaschi, J. P., additional, Tortorano, A. M., additional, Wiederhold, N. P., additional, and Turnidge, J., additional

Published
2016
Full Text
View/download PDF

2. First Report of Westerdykella dispersa as a Cause of an Angioinvasive Fungal Infection in a Neutropenic Host

Author

Sue, P. K., primary, Gurda, G. T., additional, Lee, R., additional, Watkins, T., additional, Green, R., additional, Memon, W., additional, Milstone, A. M., additional, Zelazny, A. M., additional, Fahle, G. A., additional, Pham, T. A., additional, Gibas, C. F., additional, Sutton, D. A., additional, Wickes, B. L., additional, Wiederhold, N. P., additional, and Zhang, S. X., additional

Published
2014
Full Text
View/download PDF

3. Paravertebral Mushroom: Identification of a Novel Species of Phellinus as a Human Pathogen in Chronic Granulomatous Disease

Author

De Ravin, S. S., primary, Parta, M., additional, Sutton, D. A., additional, Wickes, B. L., additional, Thompson, E. H., additional, Wiederhold, N. P., additional, Nakasone, K. K., additional, Alimchandani, M., additional, OConnell, A., additional, Notarangelo, L., additional, Kang, E., additional, Malech, H. L., additional, and Zelazny, A. M., additional

Published
2014
Full Text
View/download PDF

6. Detection and Measurement of Fungal Burden in a Guinea Pig Model of Invasive Pulmonary Aspergillosis by Novel Quantitative Nested Real-Time PCR Compared with Galactomannan and (1,3)- -D-Glucan Detection

Author

Lengerova, M., primary, Kocmanova, I., additional, Racil, Z., additional, Hrncirova, K., additional, Pospisilova, S., additional, Mayer, J., additional, Najvar, L. K., additional, Wiederhold, N. P., additional, Kirkpatrick, W. R., additional, and Patterson, T. F., additional

Published
2011
Full Text
View/download PDF

7. International Evaluation of MIC Distributions and Epidemiological Cutoff Value (ECV) Definitions for Fusarium Species Identified by Molecular Methods for the CLSI Broth Microdilution Method.

Author

Espinel-Ingroff A, Colombo AL, Cordoba S, Dufresne PJ, Fuller J, Ghannoum M, Gonzalez GM, Guarro J, Kidd SE, Meis JF, Melhem TM, Pelaez T, Pfaller MA, Szeszs MW, Takahaschi JP, Tortorano AM, Wiederhold NP, and Turnidge J

Subjects
Americas, Drug Resistance, Multiple, Fungal, Europe, Fusarium genetics, Fusarium isolation & purification, Humans, Polymerase Chain Reaction methods, Antifungal Agents pharmacology, Fusarium drug effects, Microbial Sensitivity Tests methods
Abstract

The CLSI epidemiological cutoff values (ECVs) of antifungal agents are available for various Candida spp., Aspergillus spp., and the Mucorales. However, those categorical endpoints have not been established for Fusarium spp., mostly due to the difficulties associated with collecting sufficient CLSI MICs for clinical isolates identified according to the currently recommended molecular DNA-PCR-based identification methodologies. CLSI MIC distributions were established for 53 Fusarium dimerum species complex (SC), 10 F. fujikuroi, 82 F. proliferatum, 20 F. incarnatum-F. equiseti SC, 226 F. oxysporum SC, 608 F. solani SC, and 151 F. verticillioides isolates originating in 17 laboratories (in Argentina, Australia, Brazil, Canada, Europe, Mexico, and the United States). According to the CLSI guidelines for ECV setting, ECVs encompassing ≥97.5% of pooled statistically modeled MIC distributions were as follows: for amphotericin B, 4 μg/ml (F. verticillioides) and 8 μg/ml (F. oxysporum SC and F. solani SC); for posaconazole, 2 μg/ml (F. verticillioides), 8 μg/ml (F. oxysporum SC), and 32 μg/ml (F. solani SC); for voriconazole, 4 μg/ml (F. verticillioides), 16 μg/ml (F. oxysporum SC), and 32 μg/ml (F. solani SC); and for itraconazole, 32 μg/ml (F. oxysporum SC and F. solani SC). Insufficient data precluded ECV definition for the other species. Although these ECVs could aid in detecting non-wild-type isolates with reduced susceptibility to the agents evaluated, the relationship between molecular mechanisms of resistance (gene mutations) and MICs still needs to be investigated for Fusarium spp., (Copyright © 2016, American Society for Microbiology. All Rights Reserved.)

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results