Author: "Wills, Gillian" / Publisher: american society for microbiology - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Wills, Gillian" Publisher american society for microbiology

Author: Erlwein, Otto, primary, Sweeney, Nathan P., additional, de Leon, Raffaele, additional, Wills, Gillian, additional, Robinson, Mark J., additional, and McClure, Myra O., additional
Published: 2016
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Author: Wills, Gillian S., primary, Horner, Patrick J., additional, Reynolds, Rosy, additional, Johnson, Anne M., additional, Muir, David A., additional, Brown, David W., additional, Winston, Alan, additional, Broadbent, Andrew J., additional, Parker, David, additional, and McClure, Myra O., additional
Published: 2009
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Author: Erlwein O, Sweeney NP, de Leon R, Wills G, Robinson MJ, and McClure MO
Subjects: Cell Line, DNA, Viral genetics, Gene Products, gag genetics, Genetic Therapy methods, Genetic Vectors, Humans, Endogenous Retroviruses genetics, HIV-1 genetics, Leukemia Virus, Murine genetics, Transduction, Genetic
Abstract: Sequences necessary for transduction of human endogenous retrovirus (HERV)-Kcon, a consensus of the HERV-K(HML-2) family, were analyzed and found to reside in the leader/gag region. They act in an orientation-dependent way and consist of at least two sites working together. Having defined these sequences, we exploited this information to produce a simple system to investigate to what extent virions of HERV-Kcon, murine leukemia virus, and HIV-1 have the ability to transduce each other's genomes, leading to potential contamination of gene therapy vectors., (Copyright © 2016, American Society for Microbiology. All Rights Reserved.)
Published: 2015
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