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Start Over Author "Cooper, Mr" Publisher american society of hematology
5 results on '"Cooper, Mr"'

2. The Activated Phagocyte of Polycythemia Vera

Author

Charles L. Spurr, Cooper Mr, L. R. DeChatelet, and McCall Ce

Subjects
medicine.medical_specialty, Phagocyte, Phagocytosis, Immunology, Cell Biology, Hematology, Biology, Pentose phosphate pathway, medicine.disease, Biochemistry, Polycythemia vera, Endocrinology, medicine.anatomical_structure, hemic and lymphatic diseases, Internal medicine, medicine, PANMYELOPATHY, Ingestion, O2 consumption, Metabolic activity
Abstract

Leukocytes isolated from patients with polycythemia vera (PCV), a panmyelopathy, have increased metabolic activity during the resting and phagocytizing states. Phagocytes from patients with PCV were studied by counting particle ingestion, measuring hexose monophosphate shunt (HMP) activity by the conversion of glucose-1-14C to 14CO2, and determining O2 consumption and nitroblue tetrazolium (NBT) reduction. Phagocytosis of polystyrene particles was increased. Resting glucose-1-14C activity was 6.9 ± 2.7 nmoles of glucose oxidized per hour per 5 x 106 phagocytes in normal and 16.4 ± 7.6 nmoles in polycythemia vera phagocytes. Hexose monophosphate shunt following phagocytosis increased to 50.6 ± 10.4 nmoles in normal and 91.7 ± 17.0 in polycythemia vera phagocytes (p < 0.005). Oxygen consumption was 3.6 ± 0.2 µl/hr/5 x 106 phagocytes in resting and 11.4 µl/hr/5 x 106 phagocytes in stimulated controls as compared to 4.8 ± 0.2 µl in resting and 18.4 µl in phagocytizing PCV cells (p

Published
1972
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3. Cytosine arabinoside with daunorubicin or adriamycin for therapy of acute myelocytic leukemia: a CALGB study

Author

Yates, J, primary, Glidewell, O, additional, Wiernik, P, additional, Cooper, MR, additional, Steinberg, D, additional, Dosik, H, additional, Levy, R, additional, Hoagland, C, additional, Henry, P, additional, Gottlieb, A, additional, Cornell, C, additional, Berenberg, J, additional, Hutchison, JL, additional, Raich, P, additional, Nissen, N, additional, Ellison, RR, additional, Frelick, R, additional, James, GW, additional, Falkson, G, additional, Silver, RT, additional, Haurani, F, additional, Green, M, additional, Henderson, E, additional, Leone, L, additional, and Holland, JF, additional

Published
1982
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4. Treatment of acute myelocytic leukemia: a study by cancer and leukemia group B

Author

Rai, KR, primary, Holland, JF, additional, Glidewell, OJ, additional, Weinberg, V, additional, Brunner, K, additional, Obrecht, JP, additional, Preisler, HD, additional, Nawabi, IW, additional, Prager, D, additional, Carey, RW, additional, Cooper, MR, additional, Haurani, F, additional, Hutchison, JL, additional, Silver, RT, additional, Falkson, G, additional, Wiernik, P, additional, Hoagland, HC, additional, Bloomfield, CD, additional, James, GW, additional, Gottlieb, A, additional, Ramanan, SV, additional, Blom, J, additional, Nissen, NI, additional, Bank, A, additional, Ellison, RR, additional, Kung, F, additional, Henry, P, additional, McIntyre, OR, additional, and Kaan, SK, additional

Published
1981
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