Search

Your search keyword '"Frentsch, Marco"' showing total 9 results
Start Over Author "Frentsch, Marco" Publisher american society of hematology
9 results on '"Frentsch, Marco"'

1. Single-Cell Clonal Tracking in Allogeneic Hematopoietic Stem Cell Transplantation Reveals Time Dependent and Distinct Functional Patterns in Traceable Donor T Cell Clones

Author

Wittenbecher, Friedrich, primary, Keilholz, Luisa, additional, Obermayer, Benedikt, additional, Conrad, Thomas, additional, Frentsch, Marco, additional, Blau, Igor Wolfgang, additional, Vuong, Lam Giang, additional, Borchert, Franziska, additional, Lesch, Stella, additional, Movasshagi, Kamran, additional, Tietze-Bürger, Carola, additional, Penack, Olaf, additional, Ahn, Johann, additional, Beule, Dieter, additional, Bullinger, Lars, additional, and Na, Il-Kang, additional

Published
2021
Full Text
View/download PDF

3. CD40L+ CD8+ T-Cell Dependent Antitumor Immunity

Author

Thiel, Andreas, primary, Frentsch, Marco, additional, Listopad, Joanna, additional, Stark, Regina, additional, Sada Japp, Alberto, additional, Matzmohr, Nadine, additional, Meier, Sarah, additional, Taniuchi, Ichiro, additional, and Blankenstein, Thomas, additional

Published
2014
Full Text
View/download PDF

5. CD40L expression permits CD8+ T cells to execute immunologic helper functions

Author

Frentsch, Marco, primary, Stark, Regina, additional, Matzmohr, Nadine, additional, Meier, Sarah, additional, Durlanik, Sibel, additional, Schulz, Axel R., additional, Stervbo, Ulrik, additional, Jürchott, Karsten, additional, Gebhardt, Friedemann, additional, Heine, Guido, additional, Reuter, Morgan A., additional, Betts, Michael R., additional, Busch, Dirk, additional, and Thiel, Andreas, additional

Published
2013
Full Text
View/download PDF

7. Treatment of Adenovirus Infection by Adoptive Immunotherapy: Adenovirus Capsid Hexon Is the Main Target Protein of Adenovirus-Specific Cellular Immunity.

Author

Arbach, Olga, primary, Frentsch, Marco, additional, Chmielewicz, Barbara, additional, Kaiser, Marco, additional, Ellerbrock, Heinz, additional, Lauster, Roland, additional, Arnold, Renate, additional, Radbruch, Andreas, additional, Voigt, Sebastian, additional, Ebell, Wolfram, additional, and Thiel, Andreas, additional

Published
2006
Full Text
View/download PDF

8. Adenovirus Capsid Hexon Is the Main Target Protein of Adenovirus-Specific CD4+ T-Cells: Fundamentals for Targeting Adenovirus by Adoptive Immunotherapy.

Author

Arbach, Olga, primary, Frentsch, Marco, additional, Voigt, Sebastian, additional, Chmielewicz, Barbara, additional, Kaiser, Marco, additional, Ellerbrok, Heins, additional, Lauster, Roland, additional, Radbruch, Andreas, additional, Scheffold, Alexander, additional, Ebell, Wolfram, additional, and Thiel, Andreas, additional

Published
2005
Full Text
View/download PDF

9. CD40L expression permits CD8+ T cells to execute immunologic helper functions.

Author

Frentsch, Marco, Stark, Regina, Matzmohr, Nadine, Meier, Sarah, Durlanik, Sibel, Schulz, Axel R., Stervbo, Ulrik, Jürchott, Karsten, Gebhardt, Friedemann, Heine, Guido, Reuter, Morgan A., Betts, Michael R., Busch, Dirk, and Thiel, Andreas

Subjects
*T cells, *INTRACELLULAR pathogens, *IMMUNOGENETICS, *CELL-mediated cytotoxicity, *IMMUNE response, *GENETICS
Abstract

CD8+ T cells play an essential role in immunity against intracellular pathogens, with cytotoxicity being considered their major effector mechanism. However, we here demonstrate that a major part of central and effector memory CD8+ T cells expresses CD40L, one key molecule for CD4+ T-cell-mediated help. CD40L+ CD8+ T cells are detectable among human antigen-specific immune responses, including pathogens such as influenza and yellow fever virus. CD40L+ CD8+ T cells display potent helper functions in vitro and in vivo, such as activation of antigen-presenting cells, and exhibit a cytokine expression signature similar to CD4+ T cells and unrelated to cytotoxic CD8+ T cells. The broad occurrence of CD40L+ CD8+ T cells in cellular immunity implicates that helper functions are not only executed by major histocompatibility complex (MHC) class ll-restricted CD4+ helper T cells but are also a common feature of MHC class l-restricted CD8+ T cell responses. Due to their versatile functional capacities, human CD40L+ CD8+ T cells are promising candidate cells for immune therapies, particularly when CD4+ T-cell help or pathogen-associated molecular pattern signals are limited. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results