1. A new tool for rapid and reliable diagnosis of HLA loss relapses after HSCT
- Author
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Dietrich W. Beelen, Chiara Brambati, Karin Stempelmann, Wietse Mulder, Luca Vago, Pietro Crivello, Benedetta Mazzi, Douglas A. Bost, Cinzia Pultrone, Katharina Fleischhauer, Cristina Toffalori, Fabio Ciceri, Evelien E. Bouwmans, Müberra Ahci, Ahci, Müberra, Toffalori, Cristina, Bouwmans, Evelien, Crivello, Pietro, Brambati, Chiara, Pultrone, Cinzia, Stempelmann, Karin, Bost, Dougla, Mazzi, Benedetta, Beelen, Dietrich W, Ciceri, Fabio, Mulder, Wietse, Fleischhauer, Katharina, and Vago, Luca
- Subjects
Genetic Markers ,medicine.medical_treatment ,Genes, MHC Class II ,Immunology ,Medizin ,Genes, MHC Class I ,HLA-C Antigens ,Human leukocyte antigen ,Hematopoietic stem cell transplantation ,Polymerase Chain Reaction ,Biochemistry ,03 medical and health sciences ,0302 clinical medicine ,Antigen ,Antigens, Neoplasm ,Recurrence ,Inside BLOOD Commentary ,MHC class I ,Humans ,Medicine ,HLA-DP beta-Chains ,Health Services Needs and Demand ,MHC class II ,Leukemia ,HLA-A Antigens ,biology ,business.industry ,Haplotype ,Hematopoietic Stem Cell Transplantation ,Cell Biology ,Hematology ,Histocompatibility ,surgical procedures, operative ,Haplotypes ,Tumor Escape ,030220 oncology & carcinogenesis ,Neoplastic Stem Cells ,biology.protein ,business ,Gene Deletion ,030215 immunology - Abstract
In this issue of Blood, Ahci and colleagues describe a simple and robust method for identifying the phenomenon of leukemic HLA loss often associated with treatment failure of hematopoietic stem cell transplantation from haploidentical donors (haplo-HSCT).1
- Published
- 2017
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