39 results on '"Mertens, Koen"'
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2. Whole Exome Sequencing and Extended Thrombophilia Testing in Patients with Venous Thromboembolism
3. Whole-exome sequencing in evaluation of patients with venous thromboembolism
4. Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation
5. Von Willebrand Factor Protects Factor VIII from Rapid Endocytosis Via LDL Receptor-Related Protein By Blocking the Initial Rate-Limiting Cell Surface Binding Step of Factor VIII
6. Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells
7. Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease
8. Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability
9. Factors VIII and V swap fatty feet
10. Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies
11. Modification of An Interactive Surface in the C1 Domain Reduces Immune Responses to FVIII in a Mouse Model of Hemophilia A
12. The N-Terminal Amino Acid Residues Ser764 and Lys773 of the D' Domain of Von Willebrand Factor Contribute to Factor VIII Binding
13. The Role of Factor VIII C Domains in Sorting to Weibel-Palade Bodies
14. Co-Trafficking of Coagulation Factor VIII with Von Willebrand Factor Alters the Macromolecular Structure Inside Secretory Weibel-Palade Bodies
15. Factor VII Activating Protease (FSAP): Functional Implications of the “Marburg-1” Polymorphism.
16. Platelets Contribute to Protein S Cleavage In Vivo.
17. Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity
18. Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men
19. Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles
20. Differential Anticoagulant Effects of Protein S on Vascular Cells and Platelets.
21. Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.
22. Factor VIII C1 Domain Residues 2092–2093 Participate in Membrane Binding
23. Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells
24. PEGylation or Polysialylation Reduces FVIII Binding to LRP Resulting in Prolonged Half-Life in Murine Models.
25. Antiphospholipid Antibodies with LAC Activity That Bind beta2-Glycoprotein I Cause Increased Resistance Against Activated Protein C.
26. LDL Receptor Mediates Effective Endocytosis of Activated Factor V.
27. Effective Factor VIII Endocytosis Is under Conformational Control of von Willebrand Factor.
28. Somatic Mutations in Factor VIII Inhibitors Determine Their Factor VIII Binding and Inhibitory Properties.
29. The Effect of von Willebrand Factor Normandy Mutations on Intracellular Co-Trafficking of Factor VIII to Storage Organelles.
30. Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver
31. LDL receptor cooperates with LDL receptor–related protein in regulating plasma levels of coagulation factor VIII in vivo
32. Role of Low Density Lipoprotein Receptor in the Clearance of Coagulation Factor VIII In Vivo.
33. Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor–related protein deficiency
34. 3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography
35. Multiple VH genes are used to assemble human antibodies directed toward the A3-C1 domains of factor VIII
36. Activation of factor IX zymogen results in exposure of a binding site for low-density lipoprotein receptor–related protein
37. The Life Cycle of Coagulation Factor VIII in View of Its Structure and Function
38. A Human Alloantibody Interferes With Binding of Factor IXa to the Factor VIII Light Chain
39. Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
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