1. Meningeal dissemination of retinoblastoma: CT findings in eight patients.
- Author
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Meli FJ, Boccaleri CA, Manzitti J, and Lylyk P
- Subjects
- Child, Child, Preschool, Eye Neoplasms diagnostic imaging, Female, Humans, Infant, Male, Meningeal Neoplasms diagnostic imaging, Retinoblastoma diagnostic imaging, Tomography, X-Ray Computed, Eye Neoplasms pathology, Meningeal Neoplasms secondary, Retinoblastoma secondary
- Abstract
Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache, nausea/vomiting, and restlessness were the most common symptoms. CT scans in these patients showed diffuse meningeal contrast enhancement, nodular masses, ependymal-subependymal enhancement, and ventricular dilatation. Our series of eight patients with meningeal spread illustrates a considerable range of dissemination patterns referable to retinoblastoma. One case illustrated the CT finding of multiple epidural metastases.
- Published
- 1990