1. A Review of Magnetic Particle Imaging and Perspectives on Neuroimaging
- Author
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H. Qu, Max Wintermark, Gerald A. Grant, J. Rao, L. Pisani, Gary K. Steinberg, Tonya M. Bliss, S. Huang, Kannan M. Krishnan, F. Du, Lyndia C. Wu, Guosheng Song, Michelle Y. Cheng, Timothy C. Doyle, Steven M. Conolly, and Y. Zhang
- Subjects
Superparamagnetic iron oxide nanoparticles ,Neuroimaging ,Image processing ,Perfusion scanning ,Review Article ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Magnetic particle imaging ,Inflammation imaging ,Image Processing, Computer-Assisted ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,business.industry ,Magnetic Phenomena ,Multiple applications ,equipment and supplies ,Nanoparticles ,Neurology (clinical) ,business ,human activities ,030217 neurology & neurosurgery ,Biomedical engineering - Abstract
Magnetic particle imaging is an emerging tomographic technique with the potential for simultaneous high-resolution, high-sensitivity, and real-time imaging. Magnetic particle imaging is based on the unique behavior of superparamagnetic iron oxide nanoparticles modeled by the Langevin theory, with the ability to track and quantify nanoparticle concentrations without tissue background noise. It is a promising new imaging technique for multiple applications, including vascular and perfusion imaging, oncology imaging, cell tracking, inflammation imaging, and trauma imaging. In particular, many neuroimaging applications may be enabled and enhanced with magnetic particle imaging. In this review, we will provide an overview of magnetic particle imaging principles and implementation, current applications, promising neuroimaging applications, and practical considerations.
- Published
- 2019
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