1. Cloning and Molecular Characterization of the cDNA Encoding Histone H1 From Leishmania braziliensis
- Author
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María del Carmen Thomas, E. Martinez, Ana C. González, V. Alonso, Basilio Valladares, Emma Carmelo, and A. del Castillo
- Subjects
DNA, Complementary ,Base Sequence ,Molecular Sequence Data ,Nucleic acid sequence ,Sequence Analysis, DNA ,DNA, Protozoan ,Biology ,Molecular cloning ,biology.organism_classification ,Molecular biology ,Leishmania braziliensis ,Histones ,chemistry.chemical_compound ,chemistry ,Histone H1 ,Complementary DNA ,Animals ,Parasitology ,Amino Acid Sequence ,Cloning, Molecular ,Peptide sequence ,Gene ,Ecology, Evolution, Behavior and Systematics ,DNA - Abstract
The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.
- Published
- 2002
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