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Start Over Descriptor "Isosporiasis diagnosis" Publisher american society of tropical medicine and hygiene
3 results on '"Isosporiasis diagnosis"'

2. Case Report: Molecular Diagnosis of Cystoisospora belli in a Severely Immunocompromised Patient with HIV and Kaposi Sarcoma.

Author

Iordanov RB, Leining LM, Wu M, Chan G, DiNardo AR, and Mejia R

Subjects
Anti-Infective Agents therapeutic use, Diarrhea drug therapy, Diarrhea immunology, Diarrhea parasitology, Eosinophilia drug therapy, Eosinophilia immunology, Eosinophilia parasitology, Female, Gastrointestinal Hemorrhage drug therapy, Gastrointestinal Hemorrhage immunology, Gastrointestinal Hemorrhage parasitology, HIV Infections drug therapy, HIV Infections immunology, HIV Infections parasitology, Humans, Isospora immunology, Isosporiasis drug therapy, Isosporiasis immunology, Isosporiasis parasitology, Middle Aged, Sarcoma, Kaposi drug therapy, Sarcoma, Kaposi immunology, Sarcoma, Kaposi parasitology, Treatment Outcome, Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use, Diarrhea diagnosis, Eosinophilia diagnosis, Gastrointestinal Hemorrhage diagnosis, HIV Infections diagnosis, Immunocompromised Host, Isosporiasis diagnosis, Sarcoma, Kaposi diagnosis
Abstract

Diarrhea in an immunocompromised patient has a broad infectious differential. Diagnosis is difficult despite advances in diagnostic modalities. We report a case of a 45-year-old Nigerian woman who immigrated to the United States 2 years ago. She presented to the hospital with gastrointestinal bleeding, newly diagnosed HIV, and disseminated Kaposi sarcoma. During hospitalization, the patient had an onset of watery diarrhea and high eosinophilia. Subsequent stool analysis using multi-parallel real-time quantitative polymerase chain reaction for 13 parasites was positive for Cystoisospora belli. The patient was treated with trimethoprim-sulfamethoxazole, but had relapsed disease when her antibiotics were stopped prematurely. After restarting trimethoprim-sulfamethoxazole, her diarrhea and eosinophilia improved, and she had undetectable Cystoisospora belli DNA on repeat stool quantitative polymerase chain reaction. This case highlights the importance of a thorough workup for diarrhea, including parasites, especially for immunocompromised patients. Antibiotic prophylaxis is recommended in patients with Cystoisospora belli and HIV/AIDS.

Published
2021
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3. Prevalence of intestinal parasites including microsporidia in human immunodeficiency virus-infected adults in Cameroon: a cross-sectional study.

Author

Sarfati C, Bourgeois A, Menotti J, Liegeois F, Moyou-Somo R, Delaporte E, Derouin F, Ngole EM, and Molina JM

Subjects
Adult, Animals, Cameroon epidemiology, Cross-Sectional Studies, Cryptosporidiosis diagnosis, Cryptosporidium parvum isolation & purification, Female, HIV Infections epidemiology, Humans, Isosporiasis diagnosis, Male, Microsporidiosis parasitology, Middle Aged, Polymerase Chain Reaction, Prevalence, Protozoan Infections parasitology, HIV Infections complications, Intestines parasitology, Microsporidiosis complications, Microsporidiosis epidemiology, Protozoan Infections complications, Protozoan Infections epidemiology
Abstract

To assess the prevalence of intestinal parasites in a cohort of human immunodeficiency virus (HIV)-infected adults in Cameroon, a cross-sectional study was conducted. Detection of parasites was performed in 181 stool samples from 154 HIV-infected patients with a mean CD4 cell count of 238 cells/mm(3). Only 35 patients (22%) were receiving antiretroviral therapy at the time of stool sampling, and 46 (29%) had diarrhea. Opportunistic protozoa were found in 15 patients (9.7%), 8 of whom (53%) had diarrhea. Enterocytozoon bieneusi was found in eight patients, C. parvum in six patients, and Isospora belli in three patients. All E. bieneusi isolates tested belonged to the same genotype. The prevalence of opportunistic protozoa among patients with CD4 cell counts less than 50/mm(3) was 32%.

Published
2006

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