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Your search keyword '"Farre R"' showing total 25 results
Start Over Author "Farre R" Publisher american thoracic society
25 results on '"Farre R"'

5. The Mucoid Pathobiome and Its Clinical Implications in Non-Cystic Fibrosis Bronchiectasis

Author

Fernandez-Barat, L., primary, López-Aladid, R., additional, Alcaraz, V., additional, Vázquez, N., additional, Bueno, L., additional, Pastor, R., additional, Lingren, L., additional, Sanz, H., additional, Oscanoa, P., additional, Amaro, R., additional, Motos, A., additional, Cabrera, R., additional, Vila, J., additional, Martínez, D., additional, Otero, J., additional, Farre, R., additional, Hoiby, N., additional, and Torres, A., additional

Published
2022
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17. Chronic Intermittent Hypoxia Activates Cardiac Stress-Responsive Mechanisms in a Murine Model of Sleep Apnea: Cardioprotective Effect Influenced by Age

Author

Castro-Grattoni, A.L., primary, Suarez-Giron, M.C., additional, Benitez, I., additional, Pinilla, L., additional, Tecchia, L., additional, Santamaria-Martos, F., additional, Almendros, I., additional, Farre, R., additional, Montserrat, J.M., additional, Gozal, D., additional, Barbe, F.E., additional, and Sanchez De La Torre, M., additional

Published
2019
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22. Cancer and Sleep Apnea: Cutaneous Melanoma as a Case Study.

Author

Martinez-Garcia MA, Campos-Rodriguez F, Almendros I, Garcia-Rio F, Sanchez-de-la-Torre M, Farre R, and Gozal D

Subjects
Animals, Humans, Melanoma physiopathology, Neoplasms complications, Neoplasms physiopathology, Skin Neoplasms physiopathology, Sleep Apnea, Obstructive physiopathology, Melanoma complications, Skin Neoplasms complications, Sleep Apnea, Obstructive etiology
Published
2019
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23. An Official American Thoracic Society Workshop Report: Noninvasive Identification of Inspiratory Flow Limitation in Sleep Studies.

Author

Pamidi S, Redline S, Rapoport D, Ayappa I, Palombini L, Farre R, Kirkness J, Pépin JL, Polo O, Wellman A, and Kimoff RJ

Subjects
Education, Humans, Societies, Medical, Inspiratory Capacity physiology, Sleep physiology
Abstract

This report summarizes the proceedings of the American Thoracic Society Workshop on the Noninvasive Identification of Inspiratory Flow Limitation in Sleep Studies held on May 16, 2015, in Denver, Colorado. The goal of the workshop was to discuss methods for standardizing the scoring of flow limitation from nasal cannula pressure tracings. The workshop began with presentations on the physiology underlying flow limitation, existing methods of scoring flow limitation, the effects of signal acquisition and filtering on flow shapes, and a review of the literature examining the adverse outcomes related to flow limitation. After these presentations, the results from online scoring exercises, which were crowdsourced to workshop participants in advance of the workshop, were reviewed and discussed. Break-out sessions were then held to discuss potential algorithms for scoring flow limitation. Based on these discussions, subsequent online scoring exercises, and webinars after the workshop, a consensus-based set of recommendations for a scoring algorithm for flow limitation was developed. Key conclusions from the workshop were: (1) a standardized and automated approach to scoring flow limitation is needed to provide a metric of nonepisodic elevated upper airway resistance, which can then be related to clinical outcomes in large cohorts and patient groups; (2) at this time, the most feasible method for standardization is by proposing a consensus-based framework, which includes scoring rules, developed by experts (3) hardware and software settings of acquisition devices, including filter settings, affect the shape of the flow curve, and should be clearly specified; and (4) a priority for future research is the generation of an open-source, expert-derived training set to encourage and support validation of automated flow limitation scoring algorithms.

Published
2017
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25. Association between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort.

Author

Campos-Rodriguez F, Martinez-Garcia MA, Martinez M, Duran-Cantolla J, Peña Mde L, Masdeu MJ, Gonzalez M, Campo Fd, Gallego I, Marin JM, Barbe F, Montserrat JM, and Farre R

Subjects
Age Factors, Female, Humans, Incidence, Male, Middle Aged, Retrospective Studies, Sex Factors, Spain epidemiology, Neoplasms epidemiology, Sleep Apnea, Obstructive epidemiology
Abstract

Rationale: Obstructive sleep apnea (OSA) has been associated with increased cancer mortality, but whether it is also associated with cancer incidence is unknown., Objectives: To investigate whether OSA is associated with increased cancer incidence in a large clinical cohort., Methods: A multicenter, clinical cohort study including consecutive patients investigated for suspected OSA between 2003 and 2007 in seven Spanish teaching hospitals. Apnea-hypopnea index (AHI) and percent nighttime with oxygen saturation less than 90% (TSat(90)) were used as surrogates of OSA severity, both as continuous variables and categorized by tertiles. Cox proportional hazards regression analyses were used to calculate hazard ratio (HR) and 95% confidence interval (CI) for cancer incidence after adjusting for confounding variables., Measurements and Main Results: A total of 4,910 patients were analyzed (median follow-up, 4.5 yr; interquartile range, 3.4-5.2). Compared with the lower TSat(90) category (<1.2%), the adjusted hazards (95% CI) of cancer incidence for increasing categories were 1.58 (1.07-2.34) for TSat(90) 1.2-12% and 2.33 (1.57-3.46) for TSat(90) greater than 12%. Continuous TSat(90) was also associated with cancer incidence (adjusted HR, 1.07 [1.02-1.13] per 10-unit increase in TSat(90)). In stratified analyses, TSat(90) was associated with cancer incidence in patients younger than 65 years (adjusted HR, 1.13 [95% CI, 1.06-1.21] per 10-unit increase in TSat(90)) and males (adjusted HR, 1.11 [95% CI, 1.04-1.17] per 10-unit increase in TSat(90)). AHI was not associated with cancer incidence in the adjusted analyses, except for patients younger than 65 years (adjusted HR for AHI >43 vs. <18.7, 1.66; 95% CI, 1.04-2.64)., Conclusions: Increased overnight hypoxia as a surrogate of OSA severity was associated with increased cancer incidence. This association seems to be limited to men and patients younger than 65 years of age.

Published
2013
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