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Your search keyword '"Forlini C"' showing total 6 results
Start Over Author "Forlini C" Publisher american thoracic society
6 results on '"Forlini C"'

1. Effects of Trunk Inclination on Respiratory Mechanics in Patients with COVID-19 Associated ARDS: Let's Always Report the Angle!

Author

Marrazzo, F, Spina, S, Forlini, C, Guarnieri, M, Giudici, R, Bassi, G, Bastia, L, Bottiroli, M, Fumagalli, R, Langer, T, Marrazzo, Francesco, Spina, Stefano, Forlini, Clarissa, Guarnieri, Marcello, Giudici, Riccardo, Bassi, Gabriele, Bastia, Luca, Bottiroli, Maurizio, Fumagalli, Roberto, Langer, Thomas, Marrazzo, F, Spina, S, Forlini, C, Guarnieri, M, Giudici, R, Bassi, G, Bastia, L, Bottiroli, M, Fumagalli, R, Langer, T, Marrazzo, Francesco, Spina, Stefano, Forlini, Clarissa, Guarnieri, Marcello, Giudici, Riccardo, Bassi, Gabriele, Bastia, Luca, Bottiroli, Maurizio, Fumagalli, Roberto, and Langer, Thomas

Published
2022

2. Prone Positioning during Venovenous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: A Multicentre Cohort Study and Propensity-matched Analysis

Author

Giani, M, Martucci, G, Madotto, F, Belliato, M, Fanelli, V, Garofalo, E, Forlini, C, Lucchini, A, Panarello, G, Bottino, N, Zanella, A, Fossi, F, Lissoni, A, Peroni, N, Brazzi, L, Bellani, G, Navalesi, P, Arcadipane, A, Pesenti, A, Foti, G, Grasselli, G, Giani, Marco, Martucci, Gennaro, Madotto, Fabiana, Belliato, Mirko, Fanelli, Vito, Garofalo, Eugenio, Forlini, Clarissa, Lucchini, Alberto, Panarello, Giovanna, Bottino, Nicola, Zanella, Alberto, Fossi, Francesca, Lissoni, Alfredo, Peroni, Nicola, Brazzi, Luca, Bellani, Giacomo, Navalesi, Paolo, Arcadipane, Antonio, Pesenti, Antonio, Foti, Giuseppe, Grasselli, Giacomo, Giani, M, Martucci, G, Madotto, F, Belliato, M, Fanelli, V, Garofalo, E, Forlini, C, Lucchini, A, Panarello, G, Bottino, N, Zanella, A, Fossi, F, Lissoni, A, Peroni, N, Brazzi, L, Bellani, G, Navalesi, P, Arcadipane, A, Pesenti, A, Foti, G, Grasselli, G, Giani, Marco, Martucci, Gennaro, Madotto, Fabiana, Belliato, Mirko, Fanelli, Vito, Garofalo, Eugenio, Forlini, Clarissa, Lucchini, Alberto, Panarello, Giovanna, Bottino, Nicola, Zanella, Alberto, Fossi, Francesca, Lissoni, Alfredo, Peroni, Nicola, Brazzi, Luca, Bellani, Giacomo, Navalesi, Paolo, Arcadipane, Antonio, Pesenti, Antonio, Foti, Giuseppe, and Grasselli, Giacomo

Abstract

Rationale: Prone positioning reduces mortality in patients with severe acute respiratory distress syndrome (ARDS). To date, no evidence supports the use of prone positioning (PP) during venovenous extracorporeal oxygenation (ECMO). Objectives: The aim of the study was to assess the feasibility, safety, and effect on oxygenation and lung mechanics of PP during ECMO. As a secondary exploratory aim, we assessed the association between PP and hospital mortality. Methods: We performed a multicenter retrospective cohort study in six Italian ECMO centers, including patients managed with PP during ECMO support (prone group; four centers) and patients managed in the supine position (control group; two centers). Physiological variables were analyzed at four time points (supine before PP, start of PP, end of PP, and supine after PP). The association between PP and hospital mortality was assessed by multivariate analysis and propensity score–matching. Results: A total of 240 patients were included, with 107 in the prone group and 133 in the supine group. The median duration of the 326 pronation cycles was 15 (12–18) hours. Minor reversible complications were reported in 6% of PP maneuvers. PP improved oxygenation and reduced intrapulmonary shunt. Unadjusted hospital mortality was lower in the prone group (34 vs. 50%; P = 0.017). After adjusting for covariates, PP remained significantly associated with a reduction of hospital mortality (odds ratio, 0.50; 95% confidence interval, 0.29–0.87). Sixty-six propensity score–matched patients were identified in each group. In this matched sample, patients who underwent pronation had higher ECMO duration (16 vs. 10 d; P = 0.0344) but lower hospital mortality (30% vs. 53%; P = 0.0241). Conclusions: PP during ECMO improved oxygenation and was associated with a reduction of hospital mortality.

Published
2021

3. Prone Positioning during Venovenous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Multicenter Cohort Study and Propensity-matched Analysis

Author

Fabiana Madotto, Antonio Arcadipane, Marco Giani, Alfredo Lissoni, Mirko Belliato, Antonio Pesenti, Alberto Lucchini, Giacomo Bellani, Luca Brazzi, Giuseppe Foti, Nicola Bottino, Giacomo Grasselli, Clarissa Forlini, Francesca Fossi, Eugenio Garofalo, Paolo Navalesi, Nicola Peroni, Gennaro Martucci, Giovanna Panarello, Vito Fanelli, Alberto Zanella, Giani, M, Martucci, G, Madotto, F, Belliato, M, Fanelli, V, Garofalo, E, Forlini, C, Lucchini, A, Panarello, G, Bottino, N, Zanella, A, Fossi, F, Lissoni, A, Peroni, N, Brazzi, L, Bellani, G, Navalesi, P, Arcadipane, A, Pesenti, A, Foti, G, and Grasselli, G

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, ARDS, medicine.medical_treatment, Prone positioning, Acute respiratory distress, Extracorporeal, 03 medical and health sciences, 0302 clinical medicine, mental disorders, Extracorporeal membrane oxygenation, medicine, 030212 general & internal medicine, Acute respiratory distress syndrome, business.industry, Oxygenation, medicine.disease, Prone position, surgical procedures, operative, 030228 respiratory system, Emergency medicine, Propensity score matching, ECMO, business, psychological phenomena and processes, Cohort study
Abstract

Rationale: Prone positioning reduces mortality in patients with severe acute respiratory distress syndrome (ARDS). To date, no evidence supports the use of prone positioning (PP) during venovenous extracorporeal oxygenation (ECMO). Objectives: The aim of the study was to assess the feasibility, safety, and effect on oxygenation and lung mechanics of PP during ECMO. As a secondary exploratory aim, we assessed the association between PP and hospital mortality. Methods: We performed a multicenter retrospective cohort study in six Italian ECMO centers, including patients managed with PP during ECMO support (prone group; four centers) and patients managed in the supine position (control group; two centers). Physiological variables were analyzed at four time points (supine before PP, start of PP, end of PP, and supine after PP). The association between PP and hospital mortality was assessed by multivariate analysis and propensity score–matching. Results: A total of 240 patients were included, with 107 in the prone group and 133 in the supine group. The median duration of the 326 pronation cycles was 15 (12–18) hours. Minor reversible complications were reported in 6% of PP maneuvers. PP improved oxygenation and reduced intrapulmonary shunt. Unadjusted hospital mortality was lower in the prone group (34 vs. 50%; P = 0.017). After adjusting for covariates, PP remained significantly associated with a reduction of hospital mortality (odds ratio, 0.50; 95% confidence interval, 0.29–0.87). Sixty-six propensity score–matched patients were identified in each group. In this matched sample, patients who underwent pronation had higher ECMO duration (16 vs. 10 d; P = 0.0344) but lower hospital mortality (30% vs. 53%; P = 0.0241). Conclusions: PP during ECMO improved oxygenation and was associated with a reduction of hospital mortality.

Published
2021
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4. Effects of Trunk Inclination on Respiratory Mechanics in Patients with COVID-19 Associated ARDS: Let's Always Report the Angle!

Author

Marrazzo, Francesco, Spina, Stefano, Forlini, Clarissa, Guarnieri, Marcello, Giudici, Riccardo, Bassi, Gabriele, Bastia, Luca, Bottiroli, Maurizio, Fumagalli, Roberto, Langer, Thomas, Marrazzo, F, Spina, S, Forlini, C, Guarnieri, M, Giudici, R, Bassi, G, Bastia, L, Bottiroli, M, Fumagalli, R, and Langer, T

Subjects
Mechanical ventilation, Trunk inclination, Respiratory mechanic, COVID-19, ARDS
Published
2022

5. Effects of Trunk Inclination on Respiratory Mechanics in Patients with COVID-19-associated Acute Respiratory Distress Syndrome: Let's Always Report the Angle!

Author

Marrazzo F, Spina S, Forlini C, Guarnieri M, Giudici R, Bassi G, Bastia L, Bottiroli M, Fumagalli R, and Langer T

Subjects
Aged, COVID-19 complications, Cross-Over Studies, Female, Hemodynamics, Humans, Male, Middle Aged, Pulmonary Gas Exchange, Respiratory Distress Syndrome etiology, SARS-CoV-2, COVID-19 therapy, Patient Positioning methods, Respiration, Artificial methods, Respiratory Distress Syndrome therapy, Respiratory Mechanics
Published
2022
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6. Prone Positioning during Venovenous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Multicenter Cohort Study and Propensity-matched Analysis.

Author

Giani M, Martucci G, Madotto F, Belliato M, Fanelli V, Garofalo E, Forlini C, Lucchini A, Panarello G, Bottino N, Zanella A, Fossi F, Lissoni A, Peroni N, Brazzi L, Bellani G, Navalesi P, Arcadipane A, Pesenti A, Foti G, and Grasselli G

Subjects
Cohort Studies, Humans, Prone Position, Retrospective Studies, Extracorporeal Membrane Oxygenation, Respiratory Distress Syndrome therapy
Abstract

Rationale: Prone positioning reduces mortality in patients with severe acute respiratory distress syndrome (ARDS). To date, no evidence supports the use of prone positioning (PP) during venovenous extracorporeal oxygenation (ECMO). Objectives: The aim of the study was to assess the feasibility, safety, and effect on oxygenation and lung mechanics of PP during ECMO. As a secondary exploratory aim, we assessed the association between PP and hospital mortality. Methods: We performed a multicenter retrospective cohort study in six Italian ECMO centers, including patients managed with PP during ECMO support (prone group; four centers) and patients managed in the supine position (control group; two centers). Physiological variables were analyzed at four time points (supine before PP, start of PP, end of PP, and supine after PP). The association between PP and hospital mortality was assessed by multivariate analysis and propensity score-matching. Results: A total of 240 patients were included, with 107 in the prone group and 133 in the supine group. The median duration of the 326 pronation cycles was 15 (12-18) hours. Minor reversible complications were reported in 6% of PP maneuvers. PP improved oxygenation and reduced intrapulmonary shunt. Unadjusted hospital mortality was lower in the prone group (34 vs. 50%; P  = 0.017). After adjusting for covariates, PP remained significantly associated with a reduction of hospital mortality (odds ratio, 0.50; 95% confidence interval, 0.29-0.87). Sixty-six propensity score-matched patients were identified in each group. In this matched sample, patients who underwent pronation had higher ECMO duration (16 vs. 10 d; P  = 0.0344) but lower hospital mortality (30% vs. 53%; P  = 0.0241). Conclusions: PP during ECMO improved oxygenation and was associated with a reduction of hospital mortality.

Published
2021
Full Text
View/download PDF

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