1. Cellular Source of Cysteinyl Leukotrienes Following Chlorine Exposure
- Author
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Toby K. McGovern, Soroor Farahnak, Satoshi Ano, James G. Martin, and Sarah McCuaig
- Subjects
0301 basic medicine ,Pulmonary and Respiratory Medicine ,Chemistry ,Phagocytosis ,Clinical Biochemistry ,Airway hyperresponsiveness ,chemistry.chemical_element ,CHLORINE EXPOSURE ,Cell Biology ,respiratory system ,Pharmacology ,medicine.disease_cause ,respiratory tract diseases ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,030228 respiratory system ,Cysteinyl leukotrienes ,polycyclic compounds ,Chlorine ,medicine ,Molecular Biology ,Oxidative stress - Abstract
Exposure of mice to high concentrations of chlorine leads to the synthesis of cysteinyl leukotrienes (cysLTs). CysLTs contribute to chlorine-induced airway hyperresponsiveness. The aim of the curre...
- Published
- 2020