Search

The article presents a case study of a 06-year-old bobwhite quail with necropsy. Topics include quail being confined to an open barn where the flock colony being grazed and fed a game bird maintenance feed; and intestinal mucosal lesions consisting the areas of brightly eosinophilic acute mucosal and submucosal coagulative necrosis with retention of the villous architecture.

The article presents a case study of a 10-year-old male Mastiff who was diagnosed with perianal fistulas by a local veterinarian who recommended the use of antibacterial ointment. It talks about the treatment leading to hyporexia and weight loss in the dog despite the treatment working on the lesions in the perianal skin. It tells about microscopic evaluation of the problem revealing round cells invading the adnexa and epidermis leading to the lesions.

The article presents a case study of a 30-year-old American Paint gelding horse, was admitted to the University of Tennessee Veterinary Medical Center for symptoms of colic, sweating and shaking. The horse owner administer a flunixin meglumine and brought the horse to the veterinary medical center, after its health condition failed. The article also discusses the morphologic diagnosis of pheochromocytoma of the right adrenal gland in the horse.

A letter to the editor is presented in response to the article "Sarcoma of the Proximal Portion of the Tibia in a Dog 5.5 Years After Tibial Plateau Leveling Osteotomy," by Linden Craig in the November 15, 2005 issue.

The article presents a case study of a 11-year-old domesticated male shorthair cat who was admitted to the animal hospital due to corneal ulcer and eyelid entropion. It talks about the cat having limited ocular mobility due to severe entropion along with trichiasis in the left eye. It tells about the cat loosing his appetitte and the quality of life which led to the cat being euthanized with an overdose of thiopental.

Objective--To evaluate concordance among veterinary pathologists in the assessment of histologic findings in the pars intermedia of pituitary gland sections from aged horses with mild signs suggestive of pituitary pars intermedia dysfunction (PPID). Sample Population--10 pituitary glands from aged horses. Procedure--7 pathologists were provided with signalment, clinical signs, and a single H&E-stained pituitary gland section from 10 aged horses with mild signs suggestive of PPID. Pathologists described histologic findings for each section and stated whether findings were consistent with PPID. Agreement among pathologists and with antemortem diagnostic test results was calculated. Results--Overall, only fair agreement was found among the pathologists as to which horses had histologic findings consistent with disease (mean ± SE kappa value, 0.34 ± 0.069). Interpretation of individual sections varied, with minimal agreement (4 or 5/7 pathologists) for 5 of 10 sections evaluated. Postmortem assessment was in agreement with an antemortem endocrine diagnostic test result 79% of the time. Conclusions and Clinical Relevance--Validation of antemortem diagnostic testing for PPID in horses often relies on the results of postmortem histologic evaluation. The lack of consensus in histologic interpretation of pituitary glands from aged horses with mild clinical signs in our study indicates that postmortem histologic evaluation of pituitary glands is an inappropriate standard in validation of antemortem diagnostic tests for detection of early PPID. Caution should be used when interpreting diagnostic test results in horses in which early PPID is suspected. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 14-day-old 80-kg (176-lb) male Tennessee Walking Horse was examined after the owner found it wedged under a gate earlier in the day. The article discusses that Supportive care for the colt continued with fluid therapy as previously mentioned, placement of a nasagastric tube for feedings, regular repositioning to avoid pressure sores, passive range-of-motion exercises.

In collaboration with the American College of Veterinary Pathologists.

Objective: To standardize techniques for renal scintigraphy in birds, to use scintigraphy to assess gentamicin nephrotoxicosis in birds, to compare nuclear medicine assessments with histologic assessment of gentamicin nephrotoxicosis and serum uric acid concentrations, and to determine the radiopharmaceutical that best quantifies avian renal function., Animals: 12 domestic pigeons (Columba livia domestica)., Procedure: Serum uric acid concentrations were determined for all birds. Renal scintigraphy techniques that used technetium-m99 (99mTc)-dimercaptosuccinic acid (DMSA; 4 hours after injection) and 99mTc-diethylenetriamine pentaacetic acid (DTPA; 15-minute dynamic study) were evaluated in all birds. Renal biopsy specimens were collected following baseline scans. Number and size of renal tubule granules positive for periodic acid-Schiff stain were scored for severity (scale of 0 to 4). Nephrotoxicosis was induced by administration of gentamicin. Serum uric acid concentrations were measured, and 99mTc-DMSA and 99mTc-DTPA scans were repeated after gentamicin administration. Birds were euthanatized, and complete necropsies were performed., Results: Standard avian renal scintigraphy techniques were developed for 99mTc-DMSA and 99mTc-DTPA. Decreased renal radiopharmaceutical uptake for 99mTc-DMSA and 99mTc-DTPA indicated nephrotoxicosis. Cloacal accumulation of 99mTc-DTPA was significantly decreased after administration of gentamicin. Histologic grading of renal tissue before and after gentamicin administration confirmed nephrotoxicosis. Inconsistent serum uric acid concentrations could not be used to assess nephrotoxicosis., Conclusions and Clinical Relevance: Renal nuclear scintigraphy is a useful, noninvasive means to determine renal function in birds. Although 99mTc-DMSA may prove useful in the evaluation of renal morphology, Tc-DTPA is the radiopharmaceutical agent of choice for the assessment of renal function in avian species.

Objective: To determine which imaging modality best determines the microscopic extent of primary appendicular osteosarcoma in amputated limbs in dogs., Design: Case series., Animals: 10 dogs with appendicular osteosarcoma., Procedure: 10 dogs with appendicular osteosarcoma that did not receive neoadjuvent chemotherapy were treated by use of limb amputation. Amputated limbs were imaged by use of radiography, computed tomography (CT), and magnetic resonance imaging (MRI) and examined microscopically to determine longitudinal extent of neoplastic cell involvement and length of associated intramedullary fibrosis. Changes detected by use of the various imaging studies were compared with the actual tumor length determined microscopically. Data were analyzed to determine which imaging technique most closely predicted tumor length., Results: Measurements obtained by use of craniocaudal radiographic views were most accurate at predicting tumor length but underestimated tumor length substantially in 1 limb and slightly in another limb. Measurements made by use of CT were most accurate at predicting tumor length when intramedullary fibrosis was taken into account but underestimated tumor length in 1 limb. Measurements made by use of MRI were least accurate but did not underestimate tumor length in any of the limbs., Conclusions and Clinical Relevance: Although radiography is used in diagnosis of osteosarcoma in dogs, additional imaging studies to confirm the extent of neoplasia prior to limb-sparing ostectomy may be beneficial. Underestimation of tumor length would be associated with higher incidence of incomplete excision and local tumor recurrence.