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The establishment of Taiwan Brain Tissue Resources Center (TBTRC) is extremely important for the treatment of brain neuro medicine and brain diseases in Taiwan. The clarification of legal issues or ethical disputes that have formed in it will inevitably contribute to the smooth development of TBTRC in the future. The particularly important issues such as: The relationship between the collection of brain tissue and Human Autopsy Act, the handling for use beyond the original purpose of collection, whether the donor and family members can enjoy the right to withdraw the brain tissue or specimens, etc., are all need further discussion and analysis. [ABSTRACT FROM AUTHOR]