1. Dosimetric Comparison Between Carbon-ion Radiotherapy and Photon Radiotherapy for Stage I Esophageal Cancer
- Author
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Daisaku Yoshida, Koh Imura, Yosuke Takakusagi, Kio Kano, Keisuke Tsuchida, Wataru Anno, Hiroyuki Katoh, Itsuko Serizawa, Nobutaka Mizoguchi, Shinichi Minohara, Tadashi Kamada, Yohsuke Kusano, and Yoshiki Takayama
- Subjects
Organs at Risk ,Cancer Research ,Esophageal Neoplasms ,medicine.medical_treatment ,Planning target volume ,Dose distribution ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Pharmacology ,business.industry ,Radiotherapy Planning, Computer-Assisted ,Cancer ,Radiotherapy Dosage ,Esophageal cancer ,medicine.disease ,Volumetric modulated arc therapy ,Carbon ,Stage I Esophageal Cancer ,Radiation therapy ,030220 oncology & carcinogenesis ,Carbon Ion Radiotherapy ,Radiotherapy, Intensity-Modulated ,Nuclear medicine ,business ,Research Article - Abstract
Background/aim The present study aimed to compare the radiation dose distribution of carbon-ion radiotherapy (CIRT) for stage I esophageal cancer with three-dimensional conformal radiotherapy (3DCRT) and volumetric modulated arc therapy (VMAT). Patients and methods Fifteen patients with cT1bN0M0 esophageal cancer who received 3DCRT at Kanagawa Cancer Center between January 2014 and April 2019 were enrolled. The dose-volume histogram parameters of the target volume and normal organs planned with CIRT, 3DCRT, and VMAT were evaluated. Results The homogeneity index for the target volume of CIRT was significantly lower than that of 3DCRT and VMAT. In addition, the radiation dose of CIRT to the heart, lungs, spinal cord, and skin was significantly lower than that of 3DCRT and VMAT. Conclusion Favorable dose distributions with CIRT were demonstrated compared with 3DCRT and VMAT for esophageal cancer.
- Published
- 2021
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