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Objective: Portal hypertension as an inducer of intestinal inflammatory response would cause epithelial and splanchnic vascular remodeling in the long-term. This experimental study was carried out to verify this hypothesis., Method: Structural alterations characteristic of intestinal epithelial and mesenteric vascular remodeling, the density of goblet cells and the diameter of mesenteric vein branches were studied, respectively, in rats with partial portal vein ligation in the short (1 month) and long-term (1 year)., Results: Hyperplasia of goblet cells in the small intestine (duodenum, jejunum, ileum) is maximum after 1 year of evolution of the portal hypertension and is associated with dilatation of the distal branches (3rd and 4th order) of the superior mesenteric vein., Conclusion: Long-term splanchnic remodeling in experimental portal hypertension suggests the existence of a chronic inflammatory process in this clinical condition.

Primary Effusion Lymphoma is an unusual entity and it has been described as a subset associated with human herpes virus 8 infection in homosexual males with AIDS. Its inclusion as a new entity in the Revised European-American Lymphoma Classification has been recommended. The case in which it is presented is a 47-year-old man, diagnosed with AIDS two years ago, who came with Kaposi's sarcoma. Nowadays, he has a right pleural effusion and a thoracentesis has been carried out. We obtain 10 ml of haemorrhagic fluid which is processed by standard methods. The morphologic study reveals a non-Hodgkin's lymphoma of high-grade. The immunophenotypic study shows a lymphoid neoplasm of indeterminate lineage and high proliferation index. It confirms the HHV-8 in the neoplastic cells by PCR. The diagnosis is a non-Hodgkin's lymphoma of high-grade compatible with Primary Effusion Lymphoma.