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Your search keyword '"Souza, Denise de"' showing total 3 results
Start Over Author "Souza, Denise de" Publisher associacao de medicina intensiva brasileira
3 results on '"Souza, Denise de"'

1. Qualidade de vida e desfechos em longo prazo após hospitalização por COVID-19: Protocolo para um estudo de coorte prospectivo (Coalizão VII)

Author

Rosa,Regis Goulart, Robinson,Caroline Cabral, Veiga,Viviane Cordeiro, Cavalcanti,Alexandre Biasi, Azevedo,Luciano César Pontes de, Machado,Flávia Ribeiro, Berwanger,Otavio, Avezum,Álvaro, Lopes,Renato Delascio, Lisboa,Thiago Costa, Teixeira,Cassiano, Zampieri,Fernando Godinho, Tomazini,Bruno Martins, Kawano-Dourado,Letícia, Schneider,Daniel, Souza,Denise de, Santos,Rosa da Rosa Minho dos, Silva,Sabrina Souza da, Trott,Geraldine, Gimenes,Bruna dos Passos, Souza,Ana Paula de, Barroso,Bruna Machado, Costa,Lauren Sezerá, Brognoli,Liége Gregoletto, Pelliccioli,Melissa Pezzetti, Studier,Nicole dos Santos, Schardosim,Raíne Fogliati de Carli, Haubert,Tainá Aparecida, Pallaoro,Victoria Emanuele Lobo, Oliveira,Debora Mariani de, Velho,Pedro Isaacsson, Medeiros,Gregory Saraiva, Gazzana,Marcelo Basso, Zavascki,Alexandre Prehn, Pitrez,Paulo Márcio, Oliveira,Roselaine Pinheiro de, Polanczyk,Carisi Anne, Nasi,Luiz Antônio, Hammes,Luciano Serpa, and Falavigna,Maicon

Subjects
Qualidade de vida, SARS-CoV-2, Medidas de resultados relatados pelo paciente, RC86-88.9, COVID-19, Medical emergencies. Critical care. Intensive care. First aid
Abstract

RESUMO Introdução: Os efeitos provocados pela COVID-19 em longo prazo são desconhecidos. O presente estudo tem como objetivo avaliar os fatores associados com a qualidade de vida relacionada à saúde e os desfechos em longo prazo em sobreviventes à hospitalização por COVID-19 no Brasil. Métodos: Este será um estudo multicêntrico de coorte prospectivo, aninhado em cinco ensaios clínicos randomizados desenhados para avaliar os efeitos dos tratamentos específicos para COVID-19 em mais de 50 centros no Brasil. Pacientes adultos sobreviventes à hospitalização por infecção por SARS-CoV-2 comprovada ou suspeita serão seguidos por um período de 1 ano, por meio de entrevistas telefônicas estruturadas. O desfecho primário é o escore de utilidade para qualidade de vida relacionada à saúde após 1 ano, avaliado segundo o questionário EuroQol-5D3L. Os desfechos secundários incluirão mortalidade por todas as causas, eventos cardiovasculares graves, reospitalizações, retorno ao trabalho ou estudo, condição funcional física avaliada pelo instrumento Lawton-Brody Instrumental Activities of Daily Living, dispneia avaliada segundo a escala de dispneia modificada do Medical Research Council, necessidade de suporte ventilatório em longo prazo, sintomas de ansiedade e depressão avaliados segundo a Hospital Anxiety and Depression Scale, sintomas de transtorno de estresse pós-traumático avaliados pela ferramenta Impact of Event Scale-Revised e autoavaliação da condição de saúde, conforme a Escala Visual Analógica do EuroQol-5D3L. Serão utilizadas equações de estimativas generalizada para testar a associação entre cinco conjuntos de variáveis (1 - características demográficas, 2 - condição de saúde pré-morbidade, 3 - características da doença aguda, 4 - terapias específicas para COVID-19 recebidas e 5 - variáveis pós-alta atualizadas) e desfechos. Ética e disseminação: O protocolo do estudo foi aprovado pelos Comitês de Ética em Pesquisa de todas as instituições participantes. Os resultados serão disseminados por meio de conferências e periódicos revisados por pares.

2. Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII).

Author

Rosa RG, Robinson CC, Veiga VC, Cavalcanti AB, Azevedo LCP, Machado FR, Berwanger O, Avezum Á, Lopes RD, Lisboa TC, Teixeira C, Zampieri FG, Tomazini BM, Kawano-Dourado L, Schneider D, Souza D, Santos RDRMD, Silva SSD, Trott G, Gimenes BDP, Souza AP, Barroso BM, Costa LS, Brognoli LG, Pelliccioli MP, Studier NDS, Schardosim RFC, Haubert TA, Pallaoro VEL, Oliveira DM, Velho PI, Medeiros GS, Gazzana MB, Zavascki AP, Pitrez PM, Oliveira RP, Polanczyk CA, Nasi LA, Hammes LS, and Falavigna M

Subjects
Adult, Brazil, COVID-19 mortality, Cardiovascular Diseases etiology, Cause of Death, Follow-Up Studies, Humans, Patient Readmission, Patient Reported Outcome Measures, Prospective Studies, Randomized Controlled Trials as Topic, Return to Work, Sample Size, Survivors, Telephone, COVID-19 complications, Quality of Life
Abstract

Introduction: The long-term effects caused by COVID-19 are unknown. The present study aims to assess factors associated with health-related quality of life and long-term outcomes among survivors of hospitalization for COVID-19 in Brazil., Methods: This is a multicenter prospective cohort study nested in five randomized clinical trials designed to assess the effects of specific COVID-19 treatments in over 50 centers in Brazil. Adult survivors of hospitalization due to proven or suspected SARS-CoV-2 infection will be followed-up for a period of 1 year by means of structured telephone interviews. The primary outcome is the 1-year utility score of health-related quality of life assessed by the EuroQol-5D3L. Secondary outcomes include all-cause mortality, major cardiovascular events, rehospitalizations, return to work or study, physical functional status assessed by the Lawton-Brody Instrumental Activities of Daily Living, dyspnea assessed by the modified Medical Research Council dyspnea scale, need for long-term ventilatory support, symptoms of anxiety and depression assessed by the Hospital Anxiety and Depression Scale, symptoms of posttraumatic stress disorder assessed by the Impact of Event Scale-Revised, and self-rated health assessed by the EuroQol-5D3L Visual Analog Scale. Generalized estimated equations will be performed to test the association between five sets of variables (1- demographic characteristics, 2- premorbid state of health, 3- characteristics of acute illness, 4- specific COVID-19 treatments received, and 5- time-updated postdischarge variables) and outcomes., Ethics and Dissemination: The study protocol was approved by the Research Ethics Committee of all participant institutions. The results will be disseminated through conferences and peer-reviewed journals.

Published
2021
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3. Quality of life after intensive care unit: a multicenter cohort study protocol for assessment of long-term outcomes among intensive care survivors in Brazil.

Author

Robinson CC, Rosa RG, Kochhann R, Schneider D, Sganzerla D, Dietrich C, Sanchez ÉC, Dutra FH, Oliveira MQ, Anzolin LB, Menezes SF, Jeffman R, Souza D, Silva SFD, Cruz LN, Boldo R, Cardoso JR, Birriel DC, Gamboa MN, Machado AS, Andrade JMS, Alencar C, Teixeira MC, Vieira SRR, Moreira FC, Amaral A, Silveira APM, Teles JMM, Oliveira DC, Oliveira Júnior LC, Castro LCE, Silva MSD, Neves RT, Gomes RA, Ribeiro CM, Cavalcanti AB, Oliveira RP, Maccari JG, Berto PP, Martins LA, Santos RLDS, Ue LY, Hammes LS, Sharshar T, Bozza F, Falavigna M, and Teixeira C

Subjects
Anxiety epidemiology, Brazil, Cognitive Dysfunction epidemiology, Cohort Studies, Critical Care, Depression epidemiology, Follow-Up Studies, Humans, Patient Discharge, Prevalence, Prospective Studies, Time Factors, Intensive Care Units, Quality of Life, Survivors psychology
Abstract

Objective: To establish the prevalence of physical, cognitive and psychiatric disabilities, associated factors and their relationship with the qualities of life of intensive care survivors in Brazil., Methods: A prospective multicenter cohort study is currently being conducted at 10 adult medical-surgical intensive care units representative of the 5 Brazilian geopolitical regions. Patients aged ≥ 18 years who are discharged from the participating intensive care units and stay 72 hours or more in the intensive care unit for medical or emergency surgery admissions or 120 hours or more for elective surgery admissions are consecutively included. Patients are followed up for a period of one year by means of structured telephone interviews conducted at 3, 6 and 12 months after discharge from the intensive care unit. The outcomes are functional dependence, cognitive dysfunction, anxiety and depression symptoms, posttraumatic stress symptoms, health-related quality of life, rehospitalization and long-term mortality., Discussion: The present study has the potential to contribute to current knowledge of the prevalence and factors associated with postintensive care syndrome among adult intensive care survivors in Brazil. In addition, an association might be established between postintensive care syndrome and health-related quality of life.

Published
2018
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