1. Columba S: A Scalable Co-Layout Design Automation Tool for Microfluidic Large-Scale Integration.
- Author
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Tsun-Ming Tseng, Mengchu Li, Freitas, Daniel Nestor, Mongersun, Amy, Araci, Ismail Emre, Tsung-Yi Ho, and Schlichtmann, Ulf
- Subjects
MICROFLUIDICS ,MATHEMATICAL models ,SCALABILITY ,MANUFACTURED products ,INTEGRATED circuits - Abstract
Microfluidic large-scale integration (mLSI) is a promising platform for high-throughput biological applications. Design automation for mLSI has made much progress in recent years. Columba and its succeeding work Columba 2.0 proposed a mathematical modeling method that enables automatic design of manufacturing-ready chips within minutes. However, current approaches suffer from a huge computation load when the designs become larger. Thus, in this work, we propose Columba S with a focus on scalability. Columba S applies a new architectural framework and a straight channel routing discipline, and synthesizes multiplexers for efficient and reconfigurable valve control. Experiments show that Columba S is able to generate mLSI designs with more than 200 functional units within three minutes, which enables the design of a platform for large and complex applications. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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