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Your search keyword '"Stephanno Gomes Pereira Sarmento"' showing total 2 results
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2 results on '"Stephanno Gomes Pereira Sarmento"'

1. CERVICAL PESSARY PLUS VAGINAL PROGESTERONE IN A SINGLETON PREGNANCY WITH A SHORT CERVIX: AN ANALYSIS OF EFFICACY BASED ON THE LEARNING CURVE AND CUMULATIVE SUM ANALYSIS (LC-CUSUM) IN A QUASI-RANDOMIZED CLINICAL TRIAL

Author

Antonio Fernandes Moron, A. R. Hatanaka, Tatiana K. Hamamoto, Marcelo Santucci França, Jader Cruz, Stephanno Gomes Pereira Sarmento, Julio Elito, David Baptista da Silva Pares, Valter Andrade, and Rosiane Mattar

Subjects
Pessary, Cervical pessary, medicine.medical_specialty, education.field_of_study, Singleton, Obstetrics, business.industry, Population, CUSUM, law.invention, Randomized controlled trial, Learning curve, law, medicine, Gestation, education, business
Abstract

Objective This study aims to determine the performance of cervical pessary in singleton pregnancies with a short cervix based on the learning curve. Design, Settings, Population, and Methods Between 2011 and 2018, 128 singleton gestation between 18th to 24th weeks with a short cervix (

Published
2020
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2. Improved criteria to identify risk for spontaneous preterm birth due to a short cervix

Author

Francisco Herlânio Costa Carvalho, Marcelo Santucci França, Larry J. Forney, A. R. Hatanaka, Marilza Vieira Cunha Rudge, Rosiane Mattar, Steven S. Witkin, Stephanno Gomes Pereira Sarmento, Evelyn Minis, Tatiana K. Hamamoto, Antonio Fernandes Moron, Iara M. Linhares, and Ester Cerdeira Sabino

Subjects
Gynecology, medicine.medical_specialty, Lactobacillus crispatus, biology, business.industry, biology.organism_classification, medicine.disease_cause, Cervical Length Measurement, Short cervix, Increased risk, Vaginal microbiome, Medicine, Gestation, Gardnerella vaginalis, business, Dominance (genetics)
Abstract

Objective Does the combined analysis of compounds in vaginal secretions plus vaginal microbiota composition improve the ability to predict risk for spontaneous preterm birth (SPTB) in women with a short cervix. Design Prospective observational study Setting Three hospitals in Brazil Samples Vaginal secretions from 568 women at 21-24 weeks gestation with cervical length measurement. Method Vaginal microbiome composition was determined by analysis of the V1-V3 region of the bacterial 16S ribosomal RNA gene. D- lactic acid and tissue inhibitor of matrix metalloproteinase (TIMP)-1 in vaginal secretions were measured by ELISA. Main outcome measures SPTB in relation to cervical length and dominant vaginal bacteria. Results When Lactobacillus crispatus was the dominant bacterium the concentration of TIMP-1 was lower, and D-lactic acid was higher, than when either L. iners or Gardnerella vaginalis predominated (p 1.5 ng/ml best predicted the absence of L. crispatus dominance. Vaginal levels of TIMP-1 were highest (p = 0.024) and D-lactic acid levels were lowest (p=0.032) in women with the shortest cervical length. The absence of L. crispatus dominance increased the sensitivity for predicting a SPTB from 22.4% to 81.8% or 78.3% in women with a cervical length

Published
2020
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