1. Documented 2009 H1N1 Influenza A infection in pediatric liver transplant patients--description and follow-up of 7 patients.
- Author
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Cantez MS, Gerenlı N, Hançerlı Törün S, Somer A, Salman N, and Durmaz Ö
- Subjects
- Adolescent, Antiviral Agents therapeutic use, Child, Child, Preschool, Humans, Immunosuppressive Agents adverse effects, Infant, Influenza, Human drug therapy, Influenza, Human immunology, Male, Oseltamivir therapeutic use, Retrospective Studies, Immunocompromised Host, Influenza A Virus, H1N1 Subtype, Influenza, Human virology, Liver Transplantation
- Abstract
Background/aims: There is a paucity of data regarding pediatric liver transplant patients from Turkey and less so globally. We report here 7 pediatric cases with documented H1N1 nove Influenza A infection., Material and Methods: 7 pediatric liver transplant patients on immunesuppression, tested positive with PCR for 2009 H1N1 Influenza A, have been analyzed retrospectively. All patients were commenced oseltamivir treatment and 6 patients continued to take their immunosuppressive treatment., Results: All patients (n=7) survived H1N1 novel Influenza A infection without any sequela. 1 patient has been admitted to Intensive Care Unit and has been discharged without any sequela. There was no graft dysfunction or loss during the infection episode., Conclusion: 2009 H1N1 Influenza A infection did not cause any mortality among our patients. Oseltamivir treatment may have played a role for improving in our patients' condition. Immunosuppression can be continued in pediatric liver transplant patients with close monitoring of vital signs and graft function.
- Published
- 2012
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