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Your search keyword '"Zhong, Jia-Wei"' showing total 2 results
Start Over Author "Zhong, Jia-Wei" Publisher baishideng publishing group
2 results on '"Zhong, Jia-Wei"'

1. Duodenal variceal bleeding secondary to idiopathic portal hypertension treated with transjugular intra-hepatic porto-systemic shunt plus embolization: A case report.

Author

Xie BS, Zhong JW, Wang AJ, Zhang ZD, Zhu X, and Guo GH

Abstract

Background: Duodenal varices are a lesser-known complication with non-cirrhotic portal hypertension. We report a circuitous route from missed diagnosis of duodenal varices to correction. An extremely rare case of duodenal variceal bleeding secondary to idiopathic portal hypertension (IPH) is expounded in this study, which was controlled by transjugular intra-hepatic porto-systemic shunt (TIPS) plus embolization., Case Summary: A 46-year-old woman with anemia for two years was frequently admitted to the local hospital. Upon examination, anemia was attributed to gastrointestinal tract bleeding, which resulted from duodenal variceal bleeding detected by repeated esophagogastroduodenoscopy. At the end of a complete workup, IPH leading to duodenal varices was diagnosed. Portal venography revealed that the remarked duodenal varices originated from the proximal superior mesenteric vein. TIPS plus embolization with coils and Histoacryl was performed to obliterate the rupture of duodenal varices. The anemia resolved, and the duodenal varices completely vanished by 2 mo after the initial operation., Conclusion: TIPS plus embolization may be more appropriate to treat the bleeding of large duodenal varices., Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflict of interest.

Published
2018
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2. Natural history of covert hepatic encephalopathy: An observational study of 366 cirrhotic patients.

Author

Wang AJ, Peng AP, Li BM, Gan N, Pei L, Zheng XL, Hong JB, Xiao HY, Zhong JW, and Zhu X

Subjects
Adult, Cost-Benefit Analysis, Female, Follow-Up Studies, Hepatic Encephalopathy economics, Hepatic Encephalopathy mortality, Hepatic Encephalopathy therapy, Humans, Incidence, Liver Cirrhosis economics, Liver Cirrhosis mortality, Liver Cirrhosis therapy, Male, Middle Aged, Quality of Life, Remission, Spontaneous, Triage, Hepatic Encephalopathy diagnosis, Hospitalization statistics & numerical data, Liver Cirrhosis complications, Liver Transplantation statistics & numerical data
Abstract

Aim: To explore the natural history of covert hepatic encephalopathy (CHE) in absence of medication intervention., Methods: Consecutive outpatient cirrhotic patients in a Chinese tertiary care hospital were enrolled and evaluated for CHE diagnosis. They were followed up for a mean of 11.2 ± 1.3 mo. Time to the first cirrhosis-related complications requiring hospitalization, including overt HE (OHE), resolution of CHE and death/transplantation, were compared between CHE and no-CHE patients. Predictors for complication(s) and death/transplantation were also analyzed., Results: A total of 366 patients (age: 47.2 ± 8.6 years, male: 73.0%) were enrolled. CHE was identified in 131 patients (35.8%). CHE patients had higher rates of death and incidence of complications requiring hospitalization, including OHE, compared to unimpaired patients. Moreover, 17.6% of CHE patients developed OHE, 42.0% suffered persistent CHE, and 19.8% of CHE spontaneously resolved. In CHE patients, serum albumin < 30 g/L (HR = 5.22, P = 0.03) was the sole predictor for developing OHE, and blood creatinine > 133 μmol/L (HR = 4.75, P = 0.036) predicted mortality. Child-Pugh B/C (HR = 0.084, P < 0.001) and OHE history (HR = 0.15, P = 0.014) were predictors of spontaneous resolution of CHE., Conclusion: CHE exacerbates, persists or resolves without medication intervention in clinically stable cirrhosis. Triage of patients based on these predictors will allow for more cost-effect management of CHE., Competing Interests: Conflict-of-interest statement: None of the authors has declared any conflict of interest.

Published
2017
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