1. Chinese expert consensus on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancies
- Author
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Han Liang, Hui Mian Xu, Shu Jun Yang, Guo Liang Yang, Tao Suo, Hua Qing Wang, Hong Bin Xu, Shu Zhong Cui, Zheng Gang Zhu, De Seng Wan, Lun Xiu Qin, Yun Feng Zhou, Jiafu Ji, Yan Li, Xiao Jun Yang, Shao Zhong Wei, Cong Hua Xie, and Ji Hui Hao
- Subjects
Oncology ,medicine.medical_specialty ,Colorectal cancer ,Antineoplastic Agents ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Pseudomyxoma peritonei ,Peritoneal Neoplasms ,business.industry ,General surgery ,Gastroenterology ,Expert consensus ,Minireviews ,Cytoreduction Surgical Procedures ,Hyperthermia, Induced ,General Medicine ,medicine.disease ,Combined Modality Therapy ,Peritoneal carcinomatosis ,030220 oncology & carcinogenesis ,Peritoneal mesothelioma ,030211 gastroenterology & hepatology ,Hyperthermic intraperitoneal chemotherapy ,Tomography, X-Ray Computed ,Ovarian cancer ,Cytoreductive surgery ,business - Abstract
Locoregional spread of abdominopelvic malignant tumors frequently results in peritoneal carcinomatosis (PC). The prognosis of PC patients treated by conventional systemic chemotherapy is poor, with a median survival of < 6 mo. However, over the past three decades, an integrated treatment strategy of cytoreductive surgery (CRS) + hyperthermic intraperitoneal chemotherapy (HIPEC) has been developed by the pioneering oncologists, with proved efficacy and safety in selected patients. Supported by several lines of clinical evidence from phases I, II and III clinical trials, CRS + HIPEC has been regarded as the standard treatment for selected patients with PC in many established cancer centers worldwide. In China, an expert consensus on CRS + HIPEC has been reached by the leading surgical and medical oncologists, under the framework of the China Anti-Cancer Association. This expert consensus has summarized the progress in PC clinical studies and systematically evaluated the CRS + HIPEC procedures in China as well as across the world, so as to lay the foundation for formulating PC treatment guidelines specific to the national conditions of China.
- Published
- 2016