1. Calcium Sensitizers in Cardiac Surgery: Who, When, How and Why?
- Author
-
Guerrero Orriach JL, Ramirez-Fernandez A, Escalona-Belmonte JJ, Rubio-Navarro M, and Cruz-Manas J
- Subjects
- Animals, Cardiotonic Agents adverse effects, Clinical Decision-Making, Drug Administration Schedule, Humans, Patient Selection, Perioperative Care adverse effects, Perioperative Care mortality, Postoperative Complications mortality, Postoperative Complications physiopathology, Risk Factors, Simendan adverse effects, Treatment Outcome, Vasodilator Agents adverse effects, Cardiac Surgical Procedures adverse effects, Cardiac Surgical Procedures mortality, Cardiotonic Agents administration & dosage, Perioperative Care methods, Postoperative Complications prevention & control, Simendan administration & dosage, Vasodilator Agents administration & dosage
- Abstract
Inodilators are a heterogeneous group of drugs with vasodilatory and inotropic effects. The cardioprotective effect of levosimendan is multifactorial, but now research on levosimendan is focused on the organ-protective properties of this drug in different settings, the regimen that seems to provide the greatest cardiologic and systemic benefits is early administration of levosimendan. We try to answer four questions in this review, which type of patients need this drug? what is the best time to start with it? and the best way that we could give it and finally the reasons for use it., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.)
- Published
- 2018
- Full Text
- View/download PDF