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Background: Agent negotiation is widely used in e-commerce negotiation, cloud service service-level agreements, and power transactions. However, few studies have adapted alternative negotiation models to negotiation processes between healthcare professionals and patients due to the fuzziness, ethics, and importance of medical decision making. Method: We propose a Bayesian learning based bilateral fuzzy constraint agent negotiation model (BLFCAN). It support mutually beneficial agreement on treatment between doctors and patients. The proposed model expresses the imprecise preferences and behaviors of doctors and patients through fuzzy constrained agents. To improve negotiation efficiency and social welfare, the Bayesian learning method is adopted in the proposed model to predict the opponent's preference. Results: The proposed model achieves 55.4% to 64.2% satisfaction for doctors and 69-74.5% satisfaction for patients in terms of individual satisfaction. In addition, the proposed BLFCAN can increase overall satisfaction by 26.5-29% in fewer rounds, and it can alter the negotiation strategy in a flexible manner for various negotiation scenarios. Conclusions: BLFCAN reduces communication time and cost, helps avoid potential conflicts, and reduces the impact of emotions and biases on decision-making. In addition, the BLFCAN model improves the agreement satisfaction of both parties and the total social welfare. [ABSTRACT FROM AUTHOR]

Background: The clinical practice of shared decision-making (SDM) has grown in importance. However, most studies on SDM practice concentrated on providing auxiliary knowledge from the third-party standpoint without consideration for the value preferences of doctors and patients. The essences of these methods are complete and manual negotiation, and the problems of high cost, time consumption, delayed response, and decision fatigue are serious.Methods: In response to the above limitations, this article proposes a fuzzy constraint-directed agent-based negotiation and recommendation framework for bilateral and multi-issue preference negotiation in SDM (PN-SDM). Its purpose is to provide preference information and intellectualize PN-SDM to promote SDM practice. We modeled PN-SDM problems as distributed fuzzy constraint satisfaction problems and designed the doctor agent and patient agent to negotiate on behalf of the doctor and patient. The negotiation result was then transformed into treatment plans by the recommendation model. The proposed negotiation and recommendation models were introduced in detail by an instance.Results: The proposed method with different strategies and negotiation pairs achieves good performance in terms of negotiation running time, negotiation rounds, and combined aggregated satisfaction value. Specifically, it can feasibly and effectively complete multiple rounds of PN-SDM in a few seconds and obtain higher satisfaction.Conclusion: The experimental results indicate that the negotiation model can effectively simulate preference negotiation and relieve the pressure of increasing issues. The recommendation model can assist in decision-making and help to realize SDM. In addition, it can flexibly cope with various negotiation scenarios by using different negotiation strategies (e.g., collaborative, win-win, and competitive). [ABSTRACT FROM AUTHOR]