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Background: Sphingolipid deposition in Fabry disease causes left ventricular (LV) hypertrophy, of which the accurate assessment is essential. Cardiovascular magnetic resonance (CMR) has been proposed as the gold standard. However, there is debate in the literature as to whether papillary muscles and trabeculations (P&T) should be included in LV mass (LVM). Methods/results: We examined the accuracy of 2 CMR methods of assessing LVM and LV volumes, including (MincP&T) or excluding (MexP&T) P&T, in a cohort of Fabry disease subjects (n = 20) compared to a matched control group (n = 20). Significant differences between the two measurement methods were observed for LV end-diastolic volume, LV end-systolic volume, LVM, and LV ejection fraction (LVEF) in both groups. These differences were significantly greater in the Fabry group compared to controls, except for LVEF. P&T contributed to a greater percentage of LVM in Fabry subjects than controls (20 ± 1% vs 13 ± 2%, p = 0.01). In the control group, both volume-derived methods (MincP&T or MexP&T) provided accurate SV measurements compared with the internal reference of velocity-encoded aortic flow. In the Fabry group, inclusion of P&T (MincP&T) resulted in good concordance with phase contrast flow imaging (difference between flow and volume techniques: 1 ± 3 ml, p = 0.7). Conclusion: The volumetric contribution of P&T in Fabry disease is markedly increased relative to healthy controls. Failure to account for this results in significant underestimation of LVM and results in misclassification of a proportion of subjects. [ABSTRACT FROM AUTHOR]

An abstract of the paper "Late Gadolinium Enhancement Does Occur in the Tako-Tsubo Cardiomyopathy: A Quantitative Cardiovascular Magnetic Resonance Study," by Christian Hamilton-Craig and colleagues from the 2011 SCMR/Euro CMR Joint Scientific Sessions in Nice, France from February 3-6, 2011 is presented.

The article presents an abstract on a paper titled "Non-Tropical Endomyocardial Fibrosis by Cardiovascular Magnetic Resonance, Demonstrating the Value of CMR in Restrictive Cardiomyopathy," presented at the 2011 Society for Cardiovascular Magnetic Resonance (CMR)/Euro CMR Joint Scientific Sessions held in France.

The article presents an abstract on a paper titled "Quantification of Aortic Regurgitation and Stroke Volume by CMR - Variation Due to Slice Plane Position: It Matters Where You Measure!," presented at the 2011 Society for Cardiovascular Magnetic Resonance (CMR)/Euro CMR Joint Scientific Sessions held in France.

An abstract of the paper "Quantitative Blush Evaluator (QuBE) Accurately Quantifies Microvascular Dysfunction in Patients With ST-Elevation Myocardial Infarction; Comparison With Cardiovascular Magnetic Resonance," by Italo Porto and colleagues is presented.

An abstract of the paper "CMR in the Diagnosis of Acute Pericarditis," by Nicholas J. Brett and colleagues is presented.