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Start Over Author "Kong, Juan" Publisher biomed central
7 results on '"Kong, Juan"'

6. Correlations between chromobox homolog 8 and key factors of epithelial–mesenchymal transition in hepatocellular carcinoma

Author

Zhu, Xiaonian, Luo, Wei, Bei, Chunhua, Kong, Juan, Zhang, Shidong, Fu, Yuanyuan, Li, Di, and Tan, Shengkui

Subjects
Hepatocellular carcinoma, Chromobox protein homolog 8, Primary Research, Epithelial mesenchymal transition, neoplasms, digestive system diseases, Metastasis
Abstract

Background Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in China, with high metastasis and poor prognosis. Recently, as the core component of the polycomb repressive complexes 1 (PRC1), chromobox protein homolog 8 (CBX8) is considered as an oncogene and prognostic marker in HCC. Methods A tissue microarray of 166 paired HCC and adjacent non-tumor samples were collected to identify the relationship between CBX8 and epithelial mesenchymal transition (EMT) associated proteins by Spearman correlation analysis. Knock-down of CBX8 in HCC cells was conducted to detect the biologic functions of CBX8 in HCC metastasis. Results We found out that CBX8 was over-expressed in HCC and its expression was closely related to the metastasis of HCC patients. In addition, knock-down of CBX8 was found to inhibit the invasion and migration ability of HCC cells. Moreover, there was a significant relationship between expression of CBX8 and EMT associated proteins both in HCC cells and tumor tissues. Conclusions Our results indicate that CBX8 promotes metastasis of HCC by inducing EMT process.

Published
2019

7. Correction: Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study.

Author

Wang, Ya-sen, Shen, Wei, Yang, Qing, Lin, Rong, Tang, Li-xia, Bai, Rui-miao, Yang, Dong, Zhang, Juan, Zhang, Yi-jia, Yu, Wen-ting, Song, Shi-rong, Kong, Juan, Song, Si-yu, Mao, Jian, Tong, Xiao-mei, Li, Zhan-kui, Wu, Fan, and Lin, Xin-zhu

Subjects
PREMATURE infants, FACTOR analysis, RISK assessment, CHOLESTASIS, SCIENTIFIC observation, SHORT bowel syndrome
Abstract

These should have been captured as " SP 2 sp Xiamen key laboratory of perinatal-neonatal infection, Xiamen, China"; " SP 3 sp Xiamen Clinical Research Center for Perinatal Medicine, Xiamen, China". " SP † sp Ya-sen Wang, Wei Shen, Rui-miao Bai, Juan Zhang, Wen-ting Yu, Juan Kong contributed equally to this work", however, in the published version, this was incorrectly captured as " SP † sp Ya-sen Wang, Wei Shen, Juan Zhang, Yi-jia Zhang, Shi-rong Song, Juan Kong contributed equally to this work." Jian Mao, Xiao-mei Tong, Zhan-kui Li, Fan Wu, Xin-zhu Lin are co-corresponding author on this paper, but in the published version, only Xin-zhu Lin has been captured as such. [Extracted from the article]

Published
2023
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