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Start Over Author "Li, Hailing" Publisher biomed central
11 results on '"Li, Hailing"'

3. Correction to: Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
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4. Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
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8. Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals

Author

Xing, Juan, Zhang, Zhongheng, Ke, Lu, Zhou, Jing, Qin, Bingyu, Liang, Hongkai, Chen, Xiaomei, Liu, Wenming, Liu, Zhongmin, Ai, Yuhang, Wang, Difeng, Wang, Qiuhui, Zhou, Qingshan, Zhang, Fusen, Qian, Kejian, Jiang, Dongpo, Zang, Bin, Li, Yimin, Huang, Xiaobo, Qu, Yan, Xie, Yinguang, Xu, Donglin, Zou, Zhiqiang, Zheng, Xiangde, Liu, Jianbo, Guo, Feng, Liang, Yafeng, Sun, Qiang, Gao, Hongmei, Liu, Yang, Chang, Ping, Ceng, Aibin, Yang, Rongli, Yao, Gaiqi, Sun, Yun, Wang, Xiaorong, Zhang, Yi, Wen, Yichao, Yu, Jian, Sun, Rongqing, Li, Zhiwei, Yuan, Shiying, Song, Yunlin, Gao, Peiyang, Liu, Haiyan, Zhang, Zhaohui, Wu, Yunfu, Ma, Biao, Guo, Qiang, Shan, Feng, Yang, Mingshi, Li, Hailing, Li, Yuanfei, Lu, Weihua, Wang, Lei, Qian, Chuangyun, Wang, Zhiyong, Lin, Jiandong, Zhang, Rumin, Wan, Peng, Peng, Zhiyong, Gong, Yuqiang, Huang, Linxi, Wu, Guobao, Sun, Jie, Deng, Yijun, Shi, Dongwu, Zhou, Lixin, Zhou, Fachun, Shi, Qindong, Guo, Xiaodong, Liu, Xueyan, Wu, Weidong, Meng, Xiangzhong, Li, Liandi, Chen, Weiwei, Li, Shusheng, Wan, Xianyao, Chao, Zhixin, Zhang, An, Gu, Liming, Chen, Wei, Wu, Jinglan, Zhou, Lihua, Zhang, Zhenhuan, Weng, Yibing, Feng, Yongshun, Yang, Chunli, Feng, Yongjian, Zhao, Sumin, Tong, Fei, Hao, Dong, Han, Hui, Fu, Baocai, Gong, Chuanyong, Li, Zhiping, Hu, Kunlin, Kou, Qiuye, Zhang, Han, Liu, Jie, Fan, Chuming, Zhou, Xin, Chen, Xiumei, Sun, Junli, Zhou, Xuejun, Song, Bin, Sun, Cheng, Zhao, Liyun, Dong, Xinglu, Zhang, Linlin, Tong, Dafei, Pan, Zhiguo, Cai, Chuangjie, Wang, Donghao, Dong, Yingjun, Gong, Yuanqi, Wu, Zhisong, Meng, Xinke, Wang, Ping, and Li, Weiqin

Published
2018
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9. Association of the single nucleotide polymorphism in chromosome 9p21 and chromosome 9q33 with coronary artery disease in Chinese population.

Author

Qi Li, Wenhui Peng, Hailing Li, Jianhui Zhuang, Xuesheng Luo, Yawei Xu, Li, Qi, Peng, Wenhui, Li, Hailing, Zhuang, Jianhui, Luo, Xuesheng, and Xu, Yawei

Subjects
SINGLE nucleotide polymorphisms, CORONARY disease, CORONARY angiography, CHROMOSOME abnormalities, GENOTYPES, ASIANS, CHROMOSOMES, DISEASE susceptibility, GENETIC polymorphisms, PUBLIC health surveillance, DIAGNOSIS
Abstract

Background: Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population.Methods: All patients came from the east China area and underwent coronary angiography. Rs7025486 and rs1333049 polymorphism were genotyped in 555 patients with CAD and in 480 healthy controls that underwent coronary angiography.Results: In Chinese population, the rs7025486 genotype in the case group was no significant different than the control group (P = 0.531).Meanwhile, the rs1333049 SNP has statistically significant (P = 0.006), which was the independent risk factors for CAD (OR1.252, P = 0.039), and consistent with the past studies conclusion.Conclusion: Genotype of rs1333049 on chromosome 9p21, but not rs7025486 on chromosome 9q33, is an independent determinant of the incidence of CAD in Chinese population. [ABSTRACT FROM AUTHOR]

Published
2017
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10. Association of the single nucleotide polymorphism in chromosome 9p21 and chromosome 9q33 with coronary artery disease in Chinese population.

Author

Li Q, Peng W, Li H, Zhuang J, Luo X, and Xu Y

Subjects
Aged, China epidemiology, Coronary Artery Disease diagnosis, Coronary Artery Disease epidemiology, Female, Genetic Predisposition to Disease epidemiology, Genotype, Humans, Male, Middle Aged, Asian People genetics, Chromosomes, Human, Pair 9 genetics, Coronary Artery Disease genetics, Genetic Predisposition to Disease genetics, Polymorphism, Single Nucleotide genetics, Population Surveillance methods
Abstract

Background: Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population., Methods: All patients came from the east China area and underwent coronary angiography. Rs7025486 and rs1333049 polymorphism were genotyped in 555 patients with CAD and in 480 healthy controls that underwent coronary angiography., Results: In Chinese population, the rs7025486 genotype in the case group was no significant different than the control group (P = 0.531).Meanwhile, the rs1333049 SNP has statistically significant (P = 0.006), which was the independent risk factors for CAD (OR1.252, P = 0.039), and consistent with the past studies conclusion., Conclusion: Genotype of rs1333049 on chromosome 9p21, but not rs7025486 on chromosome 9q33, is an independent determinant of the incidence of CAD in Chinese population.

Published
2017
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11. ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion.

Author

Li H, Peng W, Jian W, Li Y, Li Q, Li W, and Xu Y

Subjects
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine administration & dosage, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine pharmacology, Aged, Anti-Inflammatory Agents administration & dosage, Anti-Inflammatory Agents pharmacology, Blotting, Western, Cells, Cultured, Chemokine CCL2 blood, Chemokine CCL2 genetics, Chemotaxis, Leukocyte drug effects, China, Coculture Techniques, Diabetes Mellitus blood, Diabetes Mellitus drug therapy, Diabetes Mellitus enzymology, Diabetes Mellitus immunology, Dose-Response Relationship, Drug, Enzyme-Linked Immunosorbent Assay, Female, Gene Expression Regulation drug effects, Human Umbilical Vein Endothelial Cells enzymology, Human Umbilical Vein Endothelial Cells immunology, Humans, Infusions, Intravenous, Male, Middle Aged, Monocytes immunology, Protein Kinase Inhibitors administration & dosage, RNA, Messenger metabolism, Real-Time Polymerase Chain Reaction, Single-Blind Method, Time Factors, Vascular Cell Adhesion Molecule-1 blood, Vascular Cell Adhesion Molecule-1 genetics, rho-Associated Kinases metabolism, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine analogs & derivatives, Cell Adhesion drug effects, Chemokine CCL2 metabolism, Glucose metabolism, Human Umbilical Vein Endothelial Cells drug effects, Monocytes drug effects, Protein Kinase Inhibitors pharmacology, Vascular Cell Adhesion Molecule-1 metabolism, rho-Associated Kinases antagonists & inhibitors
Abstract

Background: Previous studies suggested that the RhoA/ROCK pathway may contribute to vascular complications in diabetes. The present study was designed to investigate whether ROCK inhibitor fasudil could prevent high glucose-induced monocyte-endothelial cells adhesion, and whether this was related to fasudil effects on vascular endothelial cell expression of chemotactic factors, vascular cell adhesion molecule-1 (VCAM-1) and monocyte chemoattractant protein-1 (MCP-1)., Methods: HUVECs were stimulated with high glucose (HG) or HG + fasudil in different concentration or different time. Monocyte-endothelial cell adhesion was determined using fluorescence-labeled monocytes. The mRNA and protein expression of VCAM-1 and MCP-1 were measured using real-time PCR and western blot. The protein levels of RhoA, ROCKI and p-MYPT were determined using western blot analysis. ELISA was employed to measure the expression of soluble VCAM-1 and MCP-1 in cell supernatants and human serum samples., Results: Fasudil significantly suppressed HG-induced adhesion of THP-1 to HUVECs. Fasudil reduced Rho/ROCK activity (as indicated by lower p-MYPT/MYPT ratio), and prevented HG induced increases in VCAM-1 and MCP-1 mRNA and protein levels. Fasudil also decreased MCP-1 concentration in HUVEC supernatants, but increased sVCAM-1 shedding into the media. In human diabetic subjects, 2 weeks of fasudil treatment significantly decreased serum MCP-1 level from 27.9 ± 10.6 pg/ml to 13.8 ± 7.0 pg/ml (P < 0.05), while sVCAM-1 increased from 23.2 ± 7.5 ng/ml to 39.7 ± 5.6 ng/ml after fasudil treatment (P < 0.05)., Conclusions: Treatment with the Rho/ROCK pathway inhibitor fasudil attenuated HG-induced monocyte-endothelial cell adhesion, possibly by reducing endothelial expression of VCAM-1 and MCP-1. These results suggest inhibition of Rho/ROCK signaling may have therapeutic potential in preventing diabetes associated vascular inflammation and atherogenesis.

Published
2012
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