20 results on '"Melville, Craig"'
Search Results
2. Understanding covid-19 outcomes among people with intellectual disabilities in England
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Sosenko, Filip, Mackay, Daniel, Pell, Jill P., Hatton, Chris, Jani, Bhautesh D., Cairns, Deborah, Ward, Laura, Henderson, Angela, Fleming, Michael, Nijhof, Dewy, and Melville, Craig
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- 2023
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3. Co-creating an intervention to promote physical activity in adolescents with intellectual disabilities: lessons learned within the Move it, Move ID!-project
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Maenhout, Laura, Verloigne, Maïté, Cairns, Deborah, Cardon, Greet, Crombez, Geert, Melville, Craig, Van Hove, Geert, and Compernolle, Sofie
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- 2023
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4. Feasibility of the Go2Play Active Play intervention for increasing physical and social development in children with intellectual disabilities
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McGarty, Arlene, Jones, Nathalie, Rutherford, Katie, Westrop, Sophie, Sutherland, Lara, Jahoda, Andrew, and Melville, Craig
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- 2021
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5. Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: protocol for a mixed-methods systematic review
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Rana, Dikshyanta, Westrop, Sophie, Germeni, Evi, McGarty, Arlene, Ells, Louisa, Lally, Phillippa, McEwan, Michael, Melville, Craig, Harris, Leanne, and Wu, Olivia
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- 2021
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6. Correlates of type 2 diabetes and glycaemic control in adults in Saudi Arabia a secondary data analysis of the Saudi health interview survey
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Al Slamah, Thamer, Nicholl, Barbara I., Alslail, Fatima Y., Harris, Leanne, Kinnear, Deborah, and Melville, Craig A.
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- 2020
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7. Systematic review: cultural adaptation and feasibility of screening for autism in non-English speaking countries
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Al Maskari, Turkiya S., Melville, Craig A., and Willis, Diane S.
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- 2018
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8. BEAT-IT: a randomised controlled trial comparing a behavioural activation treatment for depression in adults with intellectual disabilities with an attention control: summary of study protocol
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Jahoda, Andrew, Melville, Craig, Cooper, Sally-Ann, Hastings, Richard, Briggs, Andrew, Dagnan, Dave, Hatton, Chris, McConnachie, Alex, Williams, Chris, and Jones, Robert P.
- Abstract
Background:\ud Depression appears to be more enduring amongst people with intellectual disabilities, suggesting that it is a more chronic problem or more poorly managed in this population. This is not helped by a lack of evidence about the effectiveness of psychological therapies for people who have intellectual disabilities and depression. Behavioural activation, which aims to counteract depression by increasing individuals’ level of meaningful activity and their exposure to positive reinforcers, has proven to be as effective as cognitive behavioural therapy in the general population. Given that this therapy makes fewer communicative demands and focuses on activity, it was thought that behavioural activation would be both accessible and apt for people with intellectual disabilities, who are often socially marginalised.\ud \ud Methods/Design:\ud This study is a multi-centre single-blind randomised controlled trial of behavioural activation versus a self-help attention control intervention for depression in adults with mild/moderate intellectual disabilities. The study has an internal pilot in one centre, to establish that recruitment can be built up and sustained at the required level, before being rolled out across the other sites. One hundred sixty-six participants will be randomly assigned to the behavioural activation or self-help interventions, which will be delivered to individuals with mild to moderate intellectual disabilities, accompanied by someone who provides them with regular support. Both interventions are manualised and will be delivered over a period of approximately 4 months. The primary outcome measure will be the Glasgow Depression Scale, a self-report measure which is completed at baseline and 4 and 12 months post-randomisation. Secondary outcomes include measures of participants’ activity levels, proxy reports of depressive symptoms, and cost-effectiveness.\ud \ud Discussion:\ud The study will provide evidence about the effectiveness of behavioural activation for depression, adapted for people who have mild/moderate intellectual disabilities, and will inform the delivery of psychological therapies to people with intellectual disabilities in practice.
- Published
- 2015
9. A single-blind, pilot randomised trial of a weight management intervention for adults with intellectual\ud disabilities and obesity: study protocol
- Author
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Harris, Leanne, Melville, Craig A., Jones, Nathalie, Pert, Carol, Boyle, Susan, Murray, Heather, Tobin, Janet, Gray, Fiona, and Hankey, Catherine
- Abstract
Background:\ud The prevalence of obesity in adults with intellectual disabilities has consistently been reported to be higher than the general population. Despite the negative impact of obesity on health, there is little evidence of the effectiveness of weight management interventions for adults with intellectual disabilities and obesity. Preliminary results from a single-stranded feasibility study of a multi-component weight management intervention specifically designed for adults with intellectual disabilities and obesity (TAKE 5) and that satisfied clinical recommendations reported that it was acceptable to adults with intellectual disabilities and their carers. This study aims to determine the feasibility of a full-scale clinical trial of TAKE 5.\ud \ud Methods:\ud This study will follow a pilot randomised trial design. Sixty-six obese participants (body mass index (BMI) ≥30 kg/m2) will be randomly allocated to the TAKE 5 multi-component weight management intervention or a health education ‘active’ control intervention (Waist Winners Too (WWToo)). Both interventions will be delivered over a 12-month period. Participants’ anthropometric measures (body weight, BMI, waist circumference, percentage body fat); indicators of activity (levels of physical activity and sedentary behaviour) and well-being will be measured at three time points: baseline, 6 and 12 months. The researcher collecting outcome measures will be blind to study group allocation.\ud \ud Conclusions:\ud The data from this study will generate pilot data on the acceptability of randomisation, attrition rates and the estimates of patient-centred outcomes of TAKE 5, which will help inform future research and the development of a full-scale randomised clinical trial.
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- 2015
10. Process evaluation of the Walk Well study: a cluster-randomised controlled trial of a community based walking programme for adults with intellectual disabilities.
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Matthews, Lynsay, Mitchell, Fiona, Stalker, Kirsten, McConnachie, Alex, Murray, Heather, Melling, Chris, Mutrie, Nanette, and Melville, Craig
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SEDENTARY lifestyles ,HEALTH behavior ,PHYSICAL fitness ,WALKING ,INTELLECTUAL disabilities - Abstract
Background: Walking interventions can be effective in encouraging sedentary populations to become more active; however, limited research has explored the effectiveness of walking interventions for adults with intellectual disabilities. This process evaluation explored the delivery of a community based walking intervention for adults with intellectual disabilities.Methods: Walk Well was a single-blind cluster randomised controlled trial of a 12-week physical activity consultation-led walking intervention. 102 participants were randomised to the Walk Well intervention or a waiting list control group. Participants in the intervention group received three physical activity consultations with a walking advisor at baseline, 6 & 12-weeks. They were encouraged to use a pedometer to set goals and monitor their daily step count. Primary outcome was change in daily step count at 12-weeks. Process evaluation measures included qualitative interviews with key stakeholders (n = 6) and quantifiable data collected as part of the intervention. Additional process data were extracted from a sub-set of qualitative interviews with participants and carers (n = 20). Data were analysed for process information related to context, recruitment and retention, reach, implementation, and fidelity.Results: Walk Well was not effective in significantly increasing levels of physical activity. The process evaluation did, however, highlight several important areas for consideration in future studies, including: a successful recruitment and retention strategy reaching a representative sample of adults with intellectual disabilities in the community; feasible and (for most) enjoyable methods of engaging adults with intellectual disabilities in activities to support behaviour change; potential need for greater intervention duration and frequency of contact; advantages and disadvantages of using pedometers as a behaviour change tool; the need for strategies which engage carers in supporting participants; and the complex issue of 'freedom of choice' in relation to lifestyle behaviours and study participation.Conclusions: Walking interventions for adults with intellectual disabilities can be feasibly delivered in the community in relation to reach, recruitment, retention and intervention fidelity. More intensive intervention methods need to be explored as well as strategies to engage and motivate carers in their support of participants.Trial Registration: Current Controlled Trials ISRCTN50494254 (3(rd) April 2012). [ABSTRACT FROM AUTHOR]- Published
- 2016
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11. BEAT-IT: Comparing a behavioural activation treatment for depression in adults with intellectual disabilities with an attention control: study protocol for a randomised controlled trial.
- Author
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Jahoda, Andrew, Melville, Craig, Cooper, Sally-Ann, Hastings, Richard, Briggs, Andrew, Dagnan, Dave, Hatton, Chris, McConnachie, Alex, Williams, Chris, and Jones, Robert S. P.
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DIAGNOSIS of mental depression , *MENTAL depression , *THERAPEUTICS , *ATTENTION , *BEHAVIOR therapy , *COMPARATIVE studies , *COST effectiveness , *EXPERIMENTAL design , *RESEARCH methodology , *MEDICAL care costs , *MEDICAL cooperation , *RESEARCH protocols , *PEOPLE with intellectual disabilities , *PSYCHOLOGY of people with intellectual disabilities , *PSYCHOLOGICAL tests , *QUESTIONNAIRES , *RESEARCH , *TIME , *EVALUATION research , *RANDOMIZED controlled trials , *TREATMENT effectiveness , *BLIND experiment , *ECONOMICS - Abstract
Background: Depression appears to be more enduring amongst people with intellectual disabilities, suggesting that it is a more chronic problem or more poorly managed in this population. This is not helped by a lack of evidence about the effectiveness of psychological therapies for people who have intellectual disabilities and depression. Behavioural activation, which aims to counteract depression by increasing individuals' level of meaningful activity and their exposure to positive reinforcers, has proven to be as effective as cognitive behavioural therapy in the general population. Given that this therapy makes fewer communicative demands and focuses on activity, it was thought that behavioural activation would be both accessible and apt for people with intellectual disabilities, who are often socially marginalised.Methods/design: This study is a multi-centre single-blind randomised controlled trial of behavioural activation versus a self-help attention control intervention for depression in adults with mild/moderate intellectual disabilities. The study has an internal pilot in one centre, to establish that recruitment can be built up and sustained at the required level, before being rolled out across the other sites. One hundred sixty-six participants will be randomly assigned to the behavioural activation or self-help interventions, which will be delivered to individuals with mild to moderate intellectual disabilities, accompanied by someone who provides them with regular support. Both interventions are manualised and will be delivered over a period of approximately 4 months. The primary outcome measure will be the Glasgow Depression Scale, a self-report measure which is completed at baseline and 4 and 12 months post-randomisation. Secondary outcomes include measures of participants' activity levels, proxy reports of depressive symptoms, and cost-effectiveness.Discussion: The study will provide evidence about the effectiveness of behavioural activation for depression, adapted for people who have mild/moderate intellectual disabilities, and will inform the delivery of psychological therapies to people with intellectual disabilities in practice.Trial Registration: Date trial registered: Nov. 13, 2012; trial registration number: ISRCTN 09753005. [ABSTRACT FROM AUTHOR]- Published
- 2015
- Full Text
- View/download PDF
12. Effectiveness of a walking programme to support adults with intellectual disabilities to increase physical activity: walk well cluster-randomised controlled trial.
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Melville, Craig A., Mitchell, Fiona, Stalker, Kirsten, Matthews, Lynsay, McConnachie, Alex, Murray, Heather M., Melling, Chris, and Mutrie, Nanette
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BEHAVIOR modification , *CONFIDENCE intervals , *HEALTH behavior , *HEALTH promotion , *PEOPLE with intellectual disabilities , *QUESTIONNAIRES , *RESEARCH funding , *STATISTICAL sampling , *WALKING , *RANDOMIZED controlled trials , *SEDENTARY lifestyles , *PHYSICAL activity , *DATA analysis software - Abstract
Background: Programs to change health behaviours have been identified as one way to reduce health inequalities experienced by disadvantaged groups. The objective of this study was to examine the effectiveness of a behaviour change programme to increase walking and reduce sedentary behaviour of adults with intellectual disabilities. Methods: We used a cluster randomised controlled design and recruited participants over 18 years old and not regularly involved in physical activity from intellectual disabilities community-based organisations. Assessments were carried out blind to allocation. Clusters of participants were randomly allocated to the Walk Well program or a 12-week waiting list control. Walk Well consisted of three face-to-face physical activity consultations incorporating behaviour change techniques, written resources for participants and carers, and an individualised, structured walking programme. The primary outcome measured with accelerometers was change in mean step count per day between baseline and 12 weeks. Secondary outcomes included percentage time per day sedentary and in moderate-vigorous physical activity (MVPA), body mass index (BMI), and subjective well being. Results: One hundred two participants in 50 clusters were randomised. 82 (80.4 %) participants completed the primary outcome. 66.7 % of participants lived in the most deprived quintile on the Scottish Index of Multiple Deprivation. At baseline, participants walked 4780 (standard deviation 2432) steps per day, spent 65.5 % (standard deviation 10.9) of time sedentary and 59 % percent had a body mass in the obesity range. After the walking programme, the difference between mean counts of the Walk Well and control group was 69.5 steps per day [95 % confidence interval (CI) -1054 to 1193.3]. There were no significant between group differences in percentage time sedentary 1.6 % (95 % CI -2.984 to 6.102), percentage time in MVPA 0.3 % (95 % CI -0.7 to 1.3), BMI -0.2 kg/m² (95 % CI -0.8 to 0.4) or subjective well-being 0.3 (95 % CI -0.9 to 1.5). Conclusions: This is the first published trial of a walking program for adults with intellectual disabilities. Positively changing physical activity and sedentary behaviours may require more intensive programmes or upstream approaches to address the multiple social disadvantages experienced by adults with intellectual disabilities. Since participants spent the majority of their time sedentary, home-based programmes to reduce sitting time may be a viable health improvement approach. [ABSTRACT FROM AUTHOR]
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- 2015
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13. The effectiveness of psychosocial interventions for anxiety in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis.
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Kreslins, Ance, Robertson, Ashley E., and Melville, Craig
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PSYCHOSOCIAL factors ,ANXIETY in children ,TREATMENT of developmental disabilities ,AUTISM spectrum disorders ,SYSTEMATIC reviews ,META-analysis ,COGNITIVE therapy ,THERAPEUTICS - Abstract
Anxiety is a common problem in children and adolescents with autism spectrum disorder (ASD). This meta-analysis aimed to systematically evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population. Cognitive behavioural therapy (CBT) was the primary intervention modality studied. A comprehensive systematic search and study selection process was conducted. Separate statistical analyses were carried out for clinician-, parent-, and self-reported outcome measures. Sensitivity analyses were conducted by removing any outlying studies and any studies that did not use a CBT intervention. A subgroup analysis was performed to compare individual and group delivery of treatment Ten randomised control trials involving a total of 470 participants were included. The overall SMD was d = 1.05 (95 % CI 0.45, 1.65; z = 3.45, p = 0.0006) for clinician-reported outcome measures; d = 1.00 (95%CI 0.21,1.80; z = 2.47, p = 0.01) for parent-re ported outcome measures; and d = 0.65 (9596CI -0.10, 1.07; z = 1.63, p = 0.10) for self-reported outcome measures. Clinician- and pa rent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment However, the results of self-reported outcome measures failed to reach significance. The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment. The main limitations of this review were the small number of included studies as well as the clinical and methodological variability between studies. [ABSTRACT FROM AUTHOR]
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- 2015
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14. Correction: weight management interventions in adults with intellectual disabilities and obesity: a systematic review of the evidence.
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Spanos, Dimitrios, Melville, Craig Andrew, and Hankey, Catherine Ruth
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REGULATION of body weight , *INTELLECTUAL disabilities , *OVERWEIGHT persons - Abstract
A correction to the article "Weight Management Interventions in Adults With Intellectual Disabilities and Obesity: A Systematic Review of the Evidence," by Dimitrios Spanos and colleagues, published in a 2014 issue is presented.
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- 2014
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15. Weight management interventions in adults with intellectual disabilities and obesity: a systematic review of the evidence.
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Spanos, Dimitrios, Melville, Craig Andrew, and Hankey, Catherine Ruth
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BODY weight , *ANTHROPOMETRY , *ADULTS , *INTELLECTUAL disabilities , *OBESITY - Abstract
To evaluate the clinical effectiveness of weight management interventions in adults with intellectual disabilities (ID) and obesity using recommendations from current clinical guidelines for the first line management of obesity in adults. Full papers on lifestyle modification interventions published between 1982 to 2011 were sought by searching the Medline, Embase, PsycINFO and CINAHL databases. Studies were evaluated based on 1) intervention components, 2) methodology, 3) attrition rate 4) reported weight loss and 5) duration of follow up. Twenty two studies met the inclusion criteria. The interventions were classified according to inclusion of the following components: behaviour change alone, behaviour change plus physical activity, dietary advice or physical activity alone, dietary plus physical activity advice and multi-component (all three components). The majority of the studies had the same methodological limitations: no sample size justification, small heterogeneous samples, no information on randomisation methodologies. Eight studies were classified as multi-component interventions, of which one study used a 600 kilocalorie (2510 kilojoule) daily energy deficit diet. Study durations were mostly below the duration recommended in clinical guidelines and varied widely. No study included an exercise program promoting 225-300 minutes or more of moderate intensity physical activity per week but the majority of the studies used the same behaviour change techniques. Three studies reported clinically significant weight loss (≥ 5%) at six months post intervention. Current data indicate weight management interventions in those with ID differ from recommended practice and further studies to examine the effectiveness of multi-component weight management interventions for adults with ID and obesity are justified. [ABSTRACT FROM AUTHOR]
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- 2013
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16. Walk well: a randomised controlled trial of a walking intervention for adults with intellectual disabilities: study protocol.
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Mitchell, Fiona, Melville, Craig, Stalker, Kirsten, Matthews, Lynsay, McConnachie, Alex, Murray, Heather, Walker, Andrew, and Mutrie, Nanette
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- *
PHYSIOLOGICAL aspects of walking , *RANDOMIZED controlled trials , *OLDER people with disabilities , *PHYSICAL activity , *ACCELEROMETERS , *HEALTH care intervention (Social services) , *QUALITY of life - Abstract
Background: Walking interventions have been shown to have a positive impact on physical activity (PA) levels, health and wellbeing for adult and older adult populations. There has been very little work carried out to explore the effectiveness of walking interventions for adults with intellectual disabilities. This paper will provide details of the Walk Well intervention, designed for adults with intellectual disabilities, and a randomised controlled trial (RCT) to test its effectiveness. Methods/design: This study will adopt a RCT design, with participants allocated to the walking intervention group or a waiting list control group. The intervention consists of three PA consultations (baseline, six weeks and 12 weeks) and an individualised 12 week walking programme. A range of measures will be completed by participants at baseline, post intervention (three months from baseline) and at follow up (three months post intervention and six months from baseline). All outcome measures will be collected by a researcher who will be blinded to the study groups. The primary outcome will be steps walked per day, measured using accelerometers. Secondary outcome measures will include time spent in PA per day (across various intensity levels), time spent in sedentary behaviour per day, quality of life, self-efficacy and anthropometric measures to monitor weight change. Discussion: Since there are currently no published RCTs of walking interventions for adults with intellectual disabilities, this RCT will examine if a walking intervention can successfully increase PA, health and wellbeing of adults with intellectual disabilities. [ABSTRACT FROM AUTHOR]
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- 2013
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17. Clinical guidelines contribute to the health inequities experienced by individuals with intellectual disabilities.
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Mizen, Lindsay A. M., Macfie, Marjorie L., Findlay, Linda, Cooper, Sally-Ann, Melville, Craig A., and Mizen, Lindsay Am
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COGNITION disorder patients ,MEDICAL quality control ,PATHOLOGICAL psychology ,EPIDEMIOLOGY ,MEDICAL literature - Abstract
Background: Clinical practice guidelines are developed to improve the quality of healthcare. However, clinical guidelines may contribute to health inequities experienced by disadvantaged groups. This study uses an equity lens developed by the International Clinical Epidemiology Network (INCLEN) to examine how well clinical guidelines address inequities experienced by individuals with intellectual disabilities.Methods: Nine health problems relevant to the health inequities experienced by persons with intellectual disabilities were selected. Clinical guidelines on these disorders were identified from across the world. The INCLEN equity lens was used as the basis for a purpose-designed, semistructured data collection tool. Two raters independently examined each guideline and completed the data collection tool. The data extracted by each rater were discussed at a research group consensus conference and agreement was reached on a final equity lens rating for each guideline.Results: Thirty-six guidelines were identified, one of which (2.8%) explicitly excluded persons with intellectual disabilities. Of the remaining 35, six (17.1%) met the first criterion of the equity lens, identifying persons with intellectual disabilities at high risk for the specific health problem. Eight guidelines (22.9%) contained any content on intellectual disabilities. Six guidelines addressed the fourth equity lens criterion, by giving specific consideration to the barriers to implementation of the guideline in disadvantaged populations. There were no guidelines that addressed the second, third, and fifth equity lens criteria.Conclusions: The equity lens is a useful tool to systematically examine whether clinical guidelines address the health needs and inequities experienced by disadvantaged groups. Clinical guidelines are likely to further widen the health inequities experienced by persons with intellectual disabilities, and other disadvantaged groups, by being preferentially advantageous to the general population. There is a need to systematically incorporate methods to consider disadvantaged population groups into the processes used to develop clinical guidelines. [ABSTRACT FROM AUTHOR]- Published
- 2012
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18. 'Moving on and feeling good': a feasibility study to explore the lifestyle behaviours of young adults with intellectual disabilities as they transition from school to adulthood-a study protocol.
- Author
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Mitchell F, Jahoda A, Hankey C, Matthews L, Murray H, and Melville C
- Abstract
Background: The transition from adolescence to adulthood is a 'high-risk' period for weight gain in the general population. There is speculation that this may also be a risk period for adults with intellectual disabilities; however, there has been no research which has monitored change in health indicators. Since adults with intellectual disabilities have higher rates of obesity and engage in more sedentary behaviour and less physical activity than the general population, there is a need to understand more about the lifestyle behaviours of this population during the transition to adulthood. This protocol paper will provide details of the moving on and feeling good feasibility study, designed for young people with intellectual disabilities., Methods/design: A multi-point recruitment strategy will be used to recruit 30 participants with a mild-moderate level of intellectual disability. The aim of the feasibility study is to examine the feasibility of recruitment, participant retention and the measurement of relevant health behaviour outcomes. The study will assess the feasibility of monitoring weight, diet and physical activity levels in adolescents over a 12-month transitional period from school to adult life. This mixed method study will provide insight into the lives of young people with intellectual disabilities and will examine the use of Walker et al.'s social-ecological approach to promote self-determination specific to lifestyle behaviours, during this transition period. Baseline data will be collected during the final year of school, with follow-up data collection at 6 and 12 months. Anthropometric (weight, height, waist and hip circumference), objective physical activity measures (7-day accelerometer wear) and dietary and choice measures will be collected at each time point to assess the feasibility of measuring diet patterns, food frequency, physical activity and BMI. Furthermore, ten participants will be selected for short semi-structured scoping interviews at baseline and 12-month follow-up, to gain information on psychological, social and environmental factors which might affect behaviour change., Discussion: The outcomes from the feasibility study will aid the development and piloting of a sufficiently powered randomised controlled trial. This would allow us to evaluate the effectiveness and sustainability of a lifestyle behaviour intervention, over a 5-year transition period.
- Published
- 2016
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19. Feasibility of a laboratory-based accelerometer calibration protocol for children with intellectual disabilities.
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McGarty AM, Penpraze V, and Melville CA
- Abstract
Background: Accelerometry has not been calibrated for the estimation of physical activity in children with intellectual disabilities (ID), raising questions regarding the validity of interpreting accelerometer data in this population. Various protocols and criterion measures have been used in calibration studies involving typically developing (TD) children; however, the suitability of these activities and measures for children with ID is unknown. Therefore, this study aimed to test the feasibility of a laboratory-based calibration protocol for children with ID. Specifically, the feasibility of activities, measurements, and recruitment was investigated., Methods: Five children with mild to moderate ID (10.20 ± .98 years) and a comparative sample of five TD children (12.40 ± .01 years) participated in this study. Participants performed a free-living and treadmill-based activity protocol during two laboratory-based sessions. Activities were performed for 5 min and ranged from sedentary to vigorous intensity. Treadmill activities ranged from 3 to 8 km/h, and free-living activities included watching a DVD, passing a football, and jumping jacks. Resting energy expenditure was measured, and a graded exercise test was used to assess cardiorespiratory fitness. Breath-by-breath respiratory gas exchange and accelerometry were continually measured during all activities. Feasibility was assessed using observations, activity completion rates, and respiratory data., Results: All TD participants and one participant with ID completed the protocol. The physical demands of the treadmill activities affected the completion rate for participants with ID. No participant met the maximal criteria for the graded exercise test or attained a steady state during the resting measurements. Limitations were identified with the usability of respiratory gas exchange equipment and the validity of measurements. The school-based recruitment strategy was not effective, with a participation rate of 6 %. A significant ( z = 13.21, p < .0001) difference in the relationship of [Formula: see text] and accelerometry was identified between ID and TD participants., Conclusions: Due to issues with the usability and validity of breath-by-breath respiratory gas exchange and recruitment, a laboratory-based calibration protocol is currently not feasible for children with ID. An alternative field-based protocol with a non-invasive criterion measure should be considered for future studies.
- Published
- 2015
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- View/download PDF
20. A single-blind, pilot randomised trial of a weight management intervention for adults with intellectual disabilities and obesity: study protocol.
- Author
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Harris L, Melville C, Jones N, Pert C, Boyle S, Murray H, Tobin J, Gray F, and Hankey C
- Abstract
Background: The prevalence of obesity in adults with intellectual disabilities has consistently been reported to be higher than the general population. Despite the negative impact of obesity on health, there is little evidence of the effectiveness of weight management interventions for adults with intellectual disabilities and obesity. Preliminary results from a single-stranded feasibility study of a multi-component weight management intervention specifically designed for adults with intellectual disabilities and obesity (TAKE 5) and that satisfied clinical recommendations reported that it was acceptable to adults with intellectual disabilities and their carers. This study aims to determine the feasibility of a full-scale clinical trial of TAKE 5., Methods: This study will follow a pilot randomised trial design. Sixty-six obese participants (body mass index (BMI) ≥30 kg/m
2 ) will be randomly allocated to the TAKE 5 multi-component weight management intervention or a health education 'active' control intervention (Waist Winners Too (WWToo)). Both interventions will be delivered over a 12-month period. Participants' anthropometric measures (body weight, BMI, waist circumference, percentage body fat); indicators of activity (levels of physical activity and sedentary behaviour) and well-being will be measured at three time points: baseline, 6 and 12 months. The researcher collecting outcome measures will be blind to study group allocation., Conclusions: The data from this study will generate pilot data on the acceptability of randomisation, attrition rates and the estimates of patient-centred outcomes of TAKE 5, which will help inform future research and the development of a full-scale randomised clinical trial., Trial Registration: ISRCTN52903778.- Published
- 2015
- Full Text
- View/download PDF
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