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Your search keyword '"Weissert, Robert"' showing total 5 results
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5 results on '"Weissert, Robert"'

3. Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant

Author

In Vivo NMR ISI, Other research (not in main researchprogram), Jagessar, S. Anwar, Heijmans, Nicole, Blezer, Erwin L A, Bauer, Jan, Weissert, Robert, 't Hart, Bert A., In Vivo NMR ISI, Other research (not in main researchprogram), Jagessar, S. Anwar, Heijmans, Nicole, Blezer, Erwin L A, Bauer, Jan, Weissert, Robert, and 't Hart, Bert A.

Published
2015

5. NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

Author

Greve B, Hoffmann P, Vonthein R, Kun J, Lell B, Mycko MP, Selmaj KW, Berger K, Weissert R, and Kremsner PG

Subjects
Age of Onset, Autoimmunity, Case-Control Studies, Child, Gabon epidemiology, Genetic Predisposition to Disease, Germany epidemiology, Granulocytes metabolism, Humans, Malaria, Falciparum epidemiology, Malaria, Falciparum immunology, Multiple Sclerosis epidemiology, Poland epidemiology, Malaria, Falciparum genetics, Multiple Sclerosis genetics, NADPH Oxidases genetics, Pseudogenes, Reactive Oxygen Species metabolism
Abstract

Background: Neutrophil cytosolic factor 1, p47phox (NCF1) is a component of the leukocyte NADPH oxidase complex mediating formation of reactive oxygen intermediates (ROI) which play an important role in host defense and autoimmunity. An individual genomic pattern of ncf1 and its two types of pseudogenes (reflected by the DeltaGT/GTGT ratio) may influence the individual capacity to produce ROI., Methods: NCF1DeltaGT/GTGT ratios were correlated with clinical parameters and ROI production during Plasmodium falciparum malaria and with susceptibility to the autoimmune disease multiple sclerosis (MS)., Results: Among Gabonese children with severe malaria, ROI production from peripheral blood tended to be higher in individuals with a DeltaGT/GTGT ratio

Published
2008
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