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Your search keyword '"Kaminker, J."' showing total 2 results
Start Over Author "Kaminker, J." Publisher biomed central ltd
2 results on '"Kaminker, J."'

1. Apollo: a sequence annotation editor.

Author

Lewis SE, Searle SM, Harris N, Gibson M, Lyer V, Richter J, Wiel C, Bayraktaroglu L, Birney E, Crosby MA, Kaminker JS, Matthews BB, Prochnik SE, Smithy CD, Tupy JL, Rubin GM, Misra S, Mungall CJ, and Clamp ME

Subjects
Animals, Database Management Systems, Humans, User-Computer Interface, Databases, Nucleic Acid, Software Design
Abstract

The well-established inaccuracy of purely computational methods for annotating genome sequences necessitates an interactive tool to allow biological experts to refine these approximations by viewing and independently evaluating the data supporting each annotation. Apollo was developed to meet this need, enabling curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome and it is increasingly being used as a starting point for the development of customized annotation editing tools for other genome projects.

Published
2002
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2. An integrated computational pipeline and database to support whole-genome sequence annotation.

Author

Mungall CJ, Misra S, Berman BP, Carlson J, Frise E, Harris N, Marshall B, Shu S, Kaminker JS, Prochnik SE, Smith CD, Smith E, Tupy JL, Wiel C, Rubin GM, and Lewis SE

Subjects
Animals, Humans, Internet, Computational Biology methods, Databases, Genetic, Genome, Software Design
Abstract

We describe here our experience in annotating the Drosophila melanogaster genome sequence, in the course of which we developed several new open-source software tools and a database schema to support large-scale genome annotation. We have developed these into an integrated and reusable software system for whole-genome annotation. The key contributions to overall annotation quality are the marshalling of high-quality sequences for alignments and the design of a system with an adaptable and expandable flexible architecture.

Published
2002
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