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Your search keyword '"Vanderschueren, Dirk"' showing total 23 results
Start Over Author "Vanderschueren, Dirk" Publisher bioscientifica
23 results on '"Vanderschueren, Dirk"'

1. Androgen therapy does not prevent bone loss and arterial calcifications in male rats with CKD

Author

David, Karel, primary, Dubois, Vanessa, additional, Verhulst, Anja, additional, Sommers, Vera, additional, Schollaert, Dieter, additional, Deboel, Ludo, additional, Moermans, Karen, additional, Carmeliet, Geert, additional, D'Haese, Patrick, additional, Vanderschueren, Dirk, additional, Claessens, Frank, additional, Evenepoel, Pieter, additional, and Decallonne, Brigitte, additional

Published
2023
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5. Sexual symptoms predict all-cause mortality independently of sex steroids in ageing men

Author

Antonio Leen, Dejaeger Marian, Wu Frederick CW, Terence WO'Neil, Pye Stephen R, Huhtaniemi Ilpo T, Rastrelli Giulia, Forti Gianni, Casanueva Felipe F, Slowikowska-Hilczer Jolanta, Punab Margus, Vanderschueren Dirk, and Tournoy Jos

Subjects
business.industry, Ageing, Medicine, business, Sexual symptoms, All cause mortality, Demography
Published
2020

6. Fertility in men with 5-alpha reductase deficiency

Author

Devlies Wout, Joniau Steven, Antonio Leen, Claessens Frank, Van Loon Elisabet, and Vanderschueren Dirk

Subjects
medicine.medical_specialty, Endocrinology, 5-Alpha-Reductase Deficiency, media_common.quotation_subject, Internal medicine, medicine, Fertility, Biology, media_common
Published
2020

11. Free 25-hydroxyvitamin D, but not free 1.25-dihydroxyvitamin D, predicts all-cause mortality in ageing men

Author

Antonio, Leen, primary, Dejaeger, Marian, additional, Bouillon, Roger, additional, Wu, Frederick, additional, O’Neill, Terence, additional, Pye, Stephen, additional, Huhtaniemi, Ilpo, additional, Rastrelli, Giulia, additional, Forti, Gianni, additional, Casanueva, Felipe, additional, Slowikowska-Hilczer, Jolanta, additional, Punab, Margus, additional, Tournoy, Jos, additional, and Vanderschueren, Dirk, additional

Published
2020
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16. Control of androgen bioactivity by sex hormone-binding globulin

Author

Laurent, Michael R, primary, Antonio, Leen, additional, Blokland, Marco H, additional, Sterk, Saskia S, additional, Jardi, Ferran, additional, Dubois, V, additional, Kaufman, Jean-Mark, additional, Fiers, Tom, additional, Huhtaniemi, Ilpo T, additional, Hammond, Geoffrey T., additional, Vanderschueren, Dirk, additional, and Claessens, Frank, additional

Published
2016
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19. Low free testosterone is associated with hypogonadal symptoms in men with normal total testosterone levels: results from the European Male Ageing Study

Author

Antonio, Leen, primary, Wu, Frederic, additional, O'Neill, Terrence, additional, Pye, Stephen, additional, Carter, Emma, additional, Finn, Joseph, additional, Laurent, Michael, additional, Huhtaniemi, Ilpo, additional, Rutter, Martin, additional, Rastrelli, Giulia, additional, Forti, Gianni, additional, Bartfai, Gyorgy, additional, Casanueva, Felipe, additional, Kula, Krzysztof, additional, Punab, Margus, additional, Giwercman, Aleksander, additional, Claessens, Frank, additional, Decallonne, Brigitte, additional, and Vanderschueren, Dirk, additional

Published
2015
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20. Characteristics and predictors of primary hypogonadism in ageing men: longitudinal data from the European Male Ageing Study

Author

Ahern, Tomas B, primary, Huhtaniemi, Ilpo T, additional, Carter, Emma L, additional, Finn, Joseph D, additional, Pye, Stephen R, additional, O'Neill, Terence W, additional, Bartfai, Gyorgy, additional, Casanueva, Felipe F, additional, Forti, Gianni, additional, Giwercman, Aleksander, additional, Han, Thang S, additional, Kula, Krzysztof, additional, Lean, Michael EJ, additional, Pendleton, Neil, additional, Punab, Margus, additional, Vanderschueren, Dirk, additional, and Wu, Frederick C W, additional

Published
2015
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22. Liver-derived IGF1 enhances the androgenic response in prostate

Author

Svensson, Johan, primary, Kindblom, Jon, additional, Shao, Ruijin, additional, Movérare-Skrtic, Sofia, additional, Lagerquist, Marie K, additional, Andersson, Niklas, additional, Sjögren, Klara, additional, Venken, Katrien, additional, Vanderschueren, Dirk, additional, Jansson, John-Olov, additional, Isaksson, Olle, additional, and Ohlsson, Claes, additional

Published
2008
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23. Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading.

Author

Callewaert F, Sinnesael M, Gielen E, Boonen S, and Vanderschueren D

Subjects
Biomechanical Phenomena, Female, Humans, Male, Bone Development physiology, Growth Hormone metabolism, Insulin-Like Growth Factor I metabolism, Sex Characteristics
Abstract

Structural gender differences in bone mass - characterized by wider but not thicker bones - are generally attributed to opposing sex steroid actions in men and women. Recent findings have redefined the traditional concept of sex hormones as the main regulators of skeletal sexual dimorphism. GH-IGF1 action is likely to be the most important determinant of sex differences in bone mass. Estrogens limit periosteal bone expansion but stimulate endosteal bone apposition in females, whereas androgens stimulate radial bone expansion in males. Androgens not only act directly on bone through the androgen receptor (AR) but also activate estrogen receptor-α or -β (ERα or ERβ) following aromatization into estrogens. Both the AR and ERα pathways are needed to optimize radial cortical bone expansion, whereas AR signaling alone is the dominant pathway for normal male trabecular bone development. Estrogen/ERα-mediated effects in males may - at least partly - depend on interaction with IGF1. In addition, sex hormones and their receptors have an impact on the mechanical sensitivity of the growing skeleton. AR and ERβ signaling may limit the osteogenic response to loading in males and females respectively, while ERα may stimulate the response of bone to mechanical stimulation in the female skeleton. Overall, current evidence suggests that skeletal sexual dimorphism is not just the end result of differences in sex steroid secretion between the sexes, but depends on gender differences in GH-IGF1 and mechanical sensitivity to loading as well.

Published
2010
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