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1. UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model.

Author

Alfón J, Ardanaz N, Gil-Torregrosa B, Fernández A, Balsa D, Carceller E, Gómez L, Merlos M, Cortijo J, Morcillo E, and Bartrolí X

Subjects
Airway Resistance drug effects, Animals, Bronchial Hyperreactivity drug therapy, Bronchial Hyperreactivity physiopathology, Bronchoalveolar Lavage Fluid cytology, CHO Cells, Cell Count, Cricetinae, Cricetulus, Guanosine 5'-O-(3-Thiotriphosphate) pharmacology, Rats, Receptors, Histamine, Receptors, Histamine H4, Serotonin pharmacology, Anti-Asthmatic Agents pharmacology, Asthma drug therapy, Histamine Agonists pharmacology, Receptors, G-Protein-Coupled agonists
Published
2010
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