1. Impact of a terbinafine-florfenicol-betamethasone acetate otic gel on the quality of life of dogs with acute otitis externa and their owners.
- Author
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Noli C, Sartori R, and Cena T
- Subjects
- Acute Disease, Administration, Topical, Animals, Anti-Infective Agents administration & dosage, Anti-Inflammatory Agents administration & dosage, Betamethasone administration & dosage, Dogs, Drug Combinations, Female, Gels, Humans, Male, Naphthalenes administration & dosage, Otitis Externa drug therapy, Quality of Life, Terbinafine, Thiamphenicol administration & dosage, Thiamphenicol therapeutic use, Anti-Infective Agents therapeutic use, Anti-Inflammatory Agents therapeutic use, Betamethasone therapeutic use, Dog Diseases drug therapy, Naphthalenes therapeutic use, Otitis Externa veterinary, Thiamphenicol analogs & derivatives
- Abstract
Background: Treatment of canine otitis externa with owner-administered products can be difficult., Objectives: To evaluate otic treatment administered by a veterinarian on quality of life (QoL) of dogs with otitis externa and their owners, and on clinical and cytology parameters of otitis; compared to an owner-administered treatment., Animals: Fifty client-owned dogs randomly randomized into two groups and treated for 2 weeks., Methods: Veterinarians treated Group A dogs with a veterinary licensed otic gel on two occasions at a 1 week interval; owners treated Group B dogs once daily with a veterinary licensed otic drop based product along with twice weekly cleaning. Veterinarians evaluated otitis with the OTI-3 scale and semi-quantitative cytological examination on days 0, 7, 14 and 28. At each visit, owners assessed QoL with a validated questionnaire and pruritus with a Visual Analog Scale. Scores before and after treatment of each group, and differences between groups were analysed statistically., Results: In both groups, all parameters improved significantly. There was a significantly higher improvement of QoL scores, for dogs and owners, in Group A, compared to Group B at all time points (P < 0.05), except for owner QoL on Day 28. There was no difference in improvement of OTI-3 between groups at any time point, whereas Group A cytology scores and pruritus improved significantly more by Day 7 (P = 0.0026 and P = 0.0294, respectively)., Conclusion: A veterinarian-administered otic gel provided equivalent efficacy and higher QoL to dogs with otitis externa and their owners, compared to an owner-administered topical otic therapy., (© 2017 The Authors. Veterinary Dermatology published by John Wiley & Sons Ltd on behalf of the ESVD and the ACVD.)
- Published
- 2017
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