1. Spindle cell rhabdomyosarcoma of the prostate.
- Author
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Latz S, Ellinger J, Goltz D, Marx C, Leuschner I, Müller SC, and Fechner G
- Subjects
- Antineoplastic Combined Chemotherapy Protocols therapeutic use, Dactinomycin therapeutic use, Doxorubicin therapeutic use, Humans, Ifosfamide therapeutic use, Magnetic Resonance Imaging, Male, Prostate pathology, Prostatic Neoplasms drug therapy, Rhabdomyosarcoma drug therapy, Sarcoma drug therapy, Vincristine therapeutic use, Young Adult, Prostatic Neoplasms pathology, Rhabdomyosarcoma pathology, Sarcoma pathology
- Abstract
The spindle cell rhabdomyosarcoma is a rare variant of the embryonal rhabdomyosarcoma, mostly occurring in childhood. Only a few cases are described in adults. To date, no case of the spindle cell subtype of the prostatic embryonal rhabdomyosarcoma has been published. We report on a 23-year-old man, initially presenting with obstructive micturition problems, perineal pain and night sweat. After diagnosis by transrectal biopsy of the prostate, radiochemotherapy within the CWS 2002 P study was applied: nine cycles of vincristine, doxorubicin, actinomycin D, ifosfamide, and fractionated radiotherapy of the tumor and suspect lymph nodes (final dose 50.4 Gy). The tumor initially shrank, but an early local recurrence arose. Second-line chemotherapy was applied, followed by a salvage radical cytoprostatectomy. The patient died of disseminated disease 14 months after diagnosis., (© 2013 The Japanese Urological Association.)
- Published
- 2013
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