Search

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:28:16Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:32:16Z : No. of bitstreams: 1 2-s2.0-84872764879.pdf: 1974358 bytes, checksum: 3777a58ae1a490980c52d35ae5548b1a (MD5) Made available in DSpace on 2014-05-27T11:28:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-01-30 Background: Melanoacanthoma (MA) has been described in the oral mucosa as a solitary lesion or, occasionally, as multiple lesions. MA mainly affects dark skinned patients and grows rapidly, showing a plane or slightly raised appearance and a brown to black color. The differential diagnosis includes oral nevi, amalgam tattoos, and melanomas. We report here the case of a 58-year-old black woman who presented multiple pigmented lesions on the hard palate. Case presentation. Based on the differential diagnosis of melanoma, a punch biopsy (4 mm in diameter) was performed. The material was fixed in 10% formalin, embedded in paraffin, and stained with hematoxylin-eosin or submitted to immunohistochemical analysis. Immunohistochemistry using antibodies against protein S-100, melan-A, HMB-45, MCM-2, MCM-5, Ki-67 and geminin was performed. Immunohistochemical analysis revealed strong cytoplasmic immunoreactivity of dendritic melanocytes for proteinS-100, HMB-45 and melan-A.Positive staining for proliferative markers (MCM-2, MCM-5, Ki-67) was only observed in basal and suprabasal epithelial cells, confirming the reactive etiology of the lesion. The diagnosis was oral Melanoacanthoma (MA). Conclusion: The patient has been followed up for 30 months and shows no clinical alterations. MA should be included in the differential diagnosis of pigmented lesions of the oral cavity. © 2013 das Chagas e Silva de Carvalho et al.; licensee BioMed Central Ltd. Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University (UNESP), São Paulo Nanosciences and Advanced Materials Federal University of ABC, Santo André, São Paulo Department of Oral Diagnosis Piracicaba Dental School University of Campinas, Piracicaba, São Paulo Faculdade de Odontologia de São José Dos Campos - UNESP Departamento de Biociências e Diagnóstico Bucal, Av. Francisco José Longo, 777 São Dimas, 12245-000, Sao Jose dos Campos, Sao Paulo Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University (UNESP), São Paulo Faculdade de Odontologia de São José Dos Campos - UNESP Departamento de Biociências e Diagnóstico Bucal, Av. Francisco José Longo, 777 São Dimas, 12245-000, Sao Jose dos Campos, Sao Paulo

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:24:46Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:41:25Z : No. of bitstreams: 1 2-s2.0-77955292067.pdf: 4076673 bytes, checksum: 4de4ec7c299ea80d73e65b842155828f (MD5) Made available in DSpace on 2014-05-27T11:24:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-08-12 Introduction. The lateral periodontal cyst, as the name implies, occurs on a lateral periodontal location and is of developmental origin, arising from cystic degeneration of clear cells of the dental lamina. A botryoid odontogenic cyst is considered to be a rare multilocular variant of a lateral periodontal cyst. Case presentation. We report the clinical and histopathologic features of a rare case of botryoid odontogenic cyst found in an edentulous area corresponding to the right lower canine of a 64-year-old African-American woman. A multilocular radiolucency was observed, and surgical removal of the lesion revealed a nodule of rubber-like consistency measuring about 1.5 cm in diameter. Cross-sectioning of the nodule showed that it consisted of various cystic compartments. Histologically, various voluminous periodic acid-Schiff-negative clear cells randomly distributed throughout the cystic epithelium were observed, as well as cell layers showing thickenings generally formed by oval, sometimes entangled plaques. The capsule consisted of fibrous connective tissue and showed rare and discrete foci of a perivascular mononuclear inflammatory infiltrate and reactive bone-tissue fragments. The final diagnosis was botryoid odontogenic cyst. Conclusion: We provide data that allow the reader to establish the differences between botryoid odontogenic cyst, glandular odontogenic cyst, and lateral periodontal cyst, helping with the differential diagnosis. The reader will have the opportunity to review botryoid odontogenic cyst clinical and histopathologic features, including treatment. © 2010 Farina et al; licensee BioMed Central Ltd. Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University-UNESP, São José dos Campos, São Paulo Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University-UNESP, São José dos Campos, São Paulo

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:24:04Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:30:28Z : No. of bitstreams: 1 2-s2.0-74549155765.pdf: 846482 bytes, checksum: e1d3fb7351c0c85c11ac1062172c7ea9 (MD5) Made available in DSpace on 2014-05-27T11:24:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 Introduction. Osteosarcomas are highly malignant bone-forming neoplasms that account for about 20% of all sarcomas. In light of their aggressive behavior, early diagnosis is crucial for determining adequate treatment. Dental professionals may be the first to detect jaw osteosarcomas in their initial stages. The aim of this case report is to draw attention to the possibility of diagnosing this tumor based on clinical, radiographical and cytological characteristics before confirmation by histology. Case presentation. A 24-year-old Afro-Brazilian man presented with swelling and pain on the left side of the mandible in the region of the third molar (tooth 38). Radiography showed a poorly delimited intraosseous lesion with radiolucent and radiopaque areas. The cytological aspects were consistent with the diagnosis of osteosarcoma, which was confirmed by biopsy. Conclusion. Imprint cytology was found to be a reliable, rapid and easy complementary examination. An early diagnosis of osteosarcoma of the jaw is fundamental to the early determination of an adequate treatment. © 2009 Cabral et al; licensee BioMed Central Ltd. Department of Biosciences and Oral Diagnosis So José Dos Campos Dental School So Paulo State University UNESP, So José dos Campos, So Paulo Postgraduation Program in Oral Biopathology So José Dos Campos Dental School So Paulo State University UNESP, So José dos Campos, So Paulo Department of Biosciences and Oral Diagnosis So José Dos Campos Dental School So Paulo State University UNESP, So José dos Campos, So Paulo Postgraduation Program in Oral Biopathology So José Dos Campos Dental School So Paulo State University UNESP, So José dos Campos, So Paulo