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1. Age-dependent differences in the association between blood interleukin-6 levels and mortality in patients with sepsis: a retrospective observational study

Author

Takashi Shimazui, Takehiko Oami, Tadanaga Shimada, Keisuke Tomita, and Taka-aki Nakada

Subjects
Aged, Cytokines, Interleukin-6, Sepsis, Young adult, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Background Interleukin-6 (IL-6) is a cytokine that predicts clinical outcomes in critically ill patients, including those with sepsis. Elderly patients have blunted and easily dysregulated host responses to infection, which may influence IL-6 kinetics and alter the association between IL-6 levels and clinical outcomes. Methods This retrospective observational study included patients aged ≥ 16 years who were admitted to the intensive care unit at Chiba University Hospital. The patients were categorized into two groups: non-elderly (

Published
2025
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