1. The estimated healthcare cost of diabetic retinopathy in Indonesia and its projection for 2025
- Author
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Angela Nurini Agni, Sarah R. Indrayanti, Gandhi Anandika Febryanto, Arief S Kartasasmita, Muhammad Bayu Sasongko, Idhayu A. Widhasari, Felicia Widyaputri, Tri Wahyu Widayanti, Firman Setya Wardhana, Yeni Dwi Lestari, Iwan Sovani, Gitalisa Andayani Adriono, and Supanji Supanji
- Subjects
Male ,medicine.medical_specialty ,Severe NPDR ,Total cost ,Population ,Visual Acuity ,Angiogenesis Inhibitors ,030209 endocrinology & metabolism ,Type 2 diabetes ,Severity of Illness Index ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Cost of Illness ,Vitrectomy ,Health care ,Prevalence ,Humans ,Medicine ,education ,Aged ,education.field_of_study ,Diabetic Retinopathy ,Laser Coagulation ,business.industry ,Health Care Costs ,Diabetic retinopathy ,Eye screening ,Middle Aged ,Models, Theoretical ,medicine.disease ,Sensory Systems ,Ophthalmology ,Diabetes Mellitus, Type 2 ,Indonesia ,Intravitreal Injections ,Emergency medicine ,Disease Progression ,030221 ophthalmology & optometry ,Healthcare cost ,Female ,business - Abstract
PurposeTo estimate the total healthcare cost associated with diabetic retinopathy (DR) in type 2 diabetes in Indonesia and its projection for 2025.MethodsA prevalence-based cost-of-illness model was constructed from previous population-based DR study. Projection for 2025 was derived from estimated diabetes population in 2025. Direct treatment costs of DR were estimated from the perspective of healthcare. Patient perspective costs were obtained from thorough interview including only transportation cost and lost of working days related to treatment. We developed four cost-of-illness models according to DR severity level, DR without necessary treatment, needing laser treatment, laser +intravitreal (IVT) injection and laser + IVT +vitrectomy. All costs were estimated in 2017 US$.ResultsThe healthcare costs of DR in Indonesia were estimated to be $2.4 billion in 2017 and $8.9 billion in 2025. The total cost in 2017 consisted of the cost for no DR and mild–moderate non-proliferative DR (NPDR) requiring eye screening ($25.9 million), severe NPDR or proliferative DR (PDR) requiring laser treatment ($0.25 billion), severe NPDR or PDR requiring both laser and IVT injection ($1.75 billion) and advance level of PDR requiring vitrectomy ($0.44 billion).ConclusionsThe estimated healthcare cost of DR in Indonesia in 2017 was considerably high, nearly 2% of the 2017 national state budget, and projected to increase significantly to more than threefold in 2025. The highest cost may incur for DR requiring both laser and IVT injection. Therefore, public health intervention to delay or prevent severe DR may substantially reduce the healthcare cost of DR in Indonesia.
- Published
- 2019
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