1. Metastasis of malignant myoepithelial carcinoma to the brain
- Author
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Justin Clark, Stephanie M Ellens, Joshua E. Simon, Nathaniel R Ellens, and Sandra Camelo-Piragua
- Subjects
Male ,medicine.medical_specialty ,Myoepithelioma ,Unusual Association of Diseases/Symptoms ,Metastasis ,Lesion ,03 medical and health sciences ,Fatal Outcome ,0302 clinical medicine ,Biomarkers, Tumor ,medicine ,Humans ,Spinal Neoplasms ,Third ventricle ,medicine.diagnostic_test ,Brain Neoplasms ,business.industry ,Myoepithelial cell ,Neurooncology ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Salivary Gland Neoplasms ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Lymphatic Metastasis ,030220 oncology & carcinogenesis ,Carcinoma, Mucoepidermoid ,Salivary gland neoplasm ,Radiology ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
Myoepithelial tumours are a rare form of salivary gland neoplasm and intracranial metastases have rarely been described. The authors present the case of a 61-year-old patient with a history of primary myoepithelial carcinoma of the right foot. Metastases were found in the third ventricle, left temporal lobe and right frontal lobe. The third ventricular and left temporal lobe tumours were resected in a two-stage operation. Pathology of the third ventricular lesion was most consistent with metastasis. MRI of the spine 2 weeks after his operation revealed an intradural mass with several lesions in the lumbar thecal space suggesting further metastases. The patient succumbed to his disease 2 months after his two-stage operation and 5 years after his initial diagnosis. This appears to be the first case in the literature of multiple primary myoepithelial carcinoma metastases to the brain. Further information is needed to provide diagnostic and therapeutic recommendations.
- Published
- 2018