1. POEMS syndrome - a unique presentation of a rare paraneoplastic syndrome.
- Author
-
Livingston J, Cobiella C, and Hall-Craggs MA
- Subjects
- Adult, Arthroplasty, Replacement, Hip, Combined Modality Therapy, Femoral Neoplasms pathology, Femoral Neoplasms surgery, Fractures, Spontaneous pathology, Fractures, Spontaneous surgery, Hematopoietic Stem Cell Transplantation, Hip Fractures pathology, Hip Fractures surgery, Humans, Male, Neurologic Examination, POEMS Syndrome pathology, POEMS Syndrome surgery, Paraneoplastic Syndromes pathology, Paraneoplastic Syndromes surgery, Plasmacytoma pathology, Plasmacytoma surgery, Radiotherapy, Adjuvant, Femoral Neoplasms diagnosis, Fractures, Spontaneous diagnosis, Hip Fractures diagnosis, POEMS Syndrome diagnosis, Paraneoplastic Syndromes diagnosis, Plasmacytoma diagnosis, Rare Diseases
- Abstract
POEMS (peripheral neuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome is a rare multisystem paraneoplastic disorder. A 40-year-old male with a history of peripheral neuropathy and erectile dysfunction presented with a pathological fracture of the neck of the femur, found to be a solitary plasmacytoma. Additional unusual features included splenomegaly, hyperprolactinaemia and skin changes. The patient had a total hip replacement at a specialist orthopaedic hospital and is due to undergo radiotherapy to the femoral lesion and autologous stem cell transplantation.
- Published
- 2010
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