1. Islet transplantation in type 1 diabetes.
- Author
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De Kort, Hanneke, De Koning, Eelco J., Rabelink, Ton J., Bruijin, Jan A., and Bajema, Ingeborg M.
- Subjects
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TREATMENT of diabetes , *QUALITY of life , *AUTOIMMUNE diseases , *CINAHL database , *DATABASES , *DIABETES , *ENDOSCOPIC surgery , *HYPOGLYCEMIA , *INFORMATION storage & retrieval systems , *MEDICAL databases , *MEDICAL information storage & retrieval systems , *INJECTIONS , *INSULIN , *ISLANDS of Langerhans , *EVALUATION of medical care , *MEDLINE , *METABOLIC regulation , *ONLINE information services , *ORGAN donors , *PANCREAS , *PATIENT education , *SERIAL publications , *TRANSPLANTATION of organs, tissues, etc. - Abstract
The article examines the Islet transplantation as a treatment option for patients with type 1 diabetes. Currently, the transplantation of islets of Langerhans is targeted for people with severe glycaemic lability, hypoglycaemia unawareness and recurrent hypoglycaemia. It explains that type 1 diabetes is due to the autoimmune damage of insulin producing beta cells in the pancreatic islets of Langerhans. Some benefits of islet transplantation include minimal invasive and low morbidity. Reasons why islet transplantation has not become a mainstream treatment include shortage of donor organs for islet isolation, high costs of isolation procedures and the need for lifelong use of immunosuppressive agents.
- Published
- 2011
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