1. Schizophrenia: a genetic disorder of the synapse?
- Author
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Owen, Michael J., O'Donovan, Michael C, and Harrison, Paul J.
- Subjects
- *
PSYCHOSES , *SCHIZOPHRENIA , *DOPAMINE , *NEUROTRANSMITTERS , *GENES , *PATHOLOGICAL psychology - Abstract
Presents an editorial about schizophrenia. Speculation on the causes of schizophrenia; Discussion of a recent study; Hypotheses regarding dopamine and neurodevelopment; Assertion that the fundamental causes of schizophrenia are exerted from early in life and well before the changes in neurotransmission at the onset of acute psychosis; Vagueness of the hypotheses regarding schizophrenia; Need for the specific mechanisms to be identified by which the current crop of genes alters risk of schizophrenia and the molecular processes that link these primary events to altered function.
- Published
- 2005
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