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Start Over Author "Betteridge, Zoe E." Publisher bmj publishing group
4 results on '"Betteridge, Zoe E."'

1. Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Author

Rothwell, Simon, Chinoy, Hector, Lamb, Janine A., Miller, Frederick W., Rider, Lisa G., Wedderburn, Lucy R., McHugh, Neil J., Mammen, Andrew L., Betteridge, Zoe E., Tansley, Sarah L., Bowes, John, Vencovský, Ji I., Deakin, Claire T., Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M., Reed, Ann M., Molberg, Yvind, Benveniste, Olivier, Mathiesen, Pernille R., Radstake, Timothy R.D.J., Doria, Andrea, De Bleecker, Jan, Lee, Annette T., Hanna, Michael G., Machado, Pedro M., Ollier, William E., Gregersen, Peter K., Padyukov, Leonid, O'Hanlon, Terrance P., Cooper, Robert G., Lundberg, Ingrid E., Rothwell, Simon, Chinoy, Hector, Lamb, Janine A., Miller, Frederick W., Rider, Lisa G., Wedderburn, Lucy R., McHugh, Neil J., Mammen, Andrew L., Betteridge, Zoe E., Tansley, Sarah L., Bowes, John, Vencovský, Ji I., Deakin, Claire T., Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M., Reed, Ann M., Molberg, Yvind, Benveniste, Olivier, Mathiesen, Pernille R., Radstake, Timothy R.D.J., Doria, Andrea, De Bleecker, Jan, Lee, Annette T., Hanna, Michael G., Machado, Pedro M., Ollier, William E., Gregersen, Peter K., Padyukov, Leonid, O'Hanlon, Terrance P., Cooper, Robert G., and Lundberg, Ingrid E.

Published
2019

2. Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Author

UMC Utrecht, CTI Radstake, Translationele immunologie, Infection & Immunity, Rothwell, Simon, Chinoy, Hector, Lamb, Janine A., Miller, Frederick W., Rider, Lisa G., Wedderburn, Lucy R., McHugh, Neil J., Mammen, Andrew L., Betteridge, Zoe E., Tansley, Sarah L., Bowes, John, Vencovský, Ji I., Deakin, Claire T., Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M., Reed, Ann M., Molberg, Yvind, Benveniste, Olivier, Mathiesen, Pernille R., Radstake, Timothy R.D.J., Doria, Andrea, De Bleecker, Jan, Lee, Annette T., Hanna, Michael G., Machado, Pedro M., Ollier, William E., Gregersen, Peter K., Padyukov, Leonid, O'Hanlon, Terrance P., Cooper, Robert G., Lundberg, Ingrid E., UMC Utrecht, CTI Radstake, Translationele immunologie, Infection & Immunity, Rothwell, Simon, Chinoy, Hector, Lamb, Janine A., Miller, Frederick W., Rider, Lisa G., Wedderburn, Lucy R., McHugh, Neil J., Mammen, Andrew L., Betteridge, Zoe E., Tansley, Sarah L., Bowes, John, Vencovský, Ji I., Deakin, Claire T., Dankó, Katalin, Vidya, Limaye, Selva-O'Callaghan, Albert, Pachman, Lauren M., Reed, Ann M., Molberg, Yvind, Benveniste, Olivier, Mathiesen, Pernille R., Radstake, Timothy R.D.J., Doria, Andrea, De Bleecker, Jan, Lee, Annette T., Hanna, Michael G., Machado, Pedro M., Ollier, William E., Gregersen, Peter K., Padyukov, Leonid, O'Hanlon, Terrance P., Cooper, Robert G., and Lundberg, Ingrid E.

Published
2019

3. The EuroMyositis registry: an international collaborative tool to facilitate myositis research

Author

Lilleker, James B; https://orcid.org/0000-0002-9230-4137, Vencovsky, Jiri; https://orcid.org/0000-0002-0851-0713, Wang, Guochun, Wedderburn, Lucy R, Diederichsen, Louise Pyndt; https://orcid.org/0000-0002-2581-8912, Schmidt, Jens, Oakley, Paula, Benveniste, Olivier, Danieli, Maria Giovanna; https://orcid.org/0000-0002-9608-2252, Danko, Katalin, Thuy, Nguyen Thi Phuong, Vazquez-Del Mercado, Monica, Andersson, Helena, De Paepe, Boel, deBleecker, Jan L, Maurer, Britta, McCann, Liza J, Pipitone, Nicolo, McHugh, Neil, Betteridge, Zoe E, New, Paul, Cooper, Robert G, Ollier, William E, Lamb, Janine A, Krogh, Niels Steen, Lundberg, Ingrid E, Chinoy, Hector, Lilleker, James B; https://orcid.org/0000-0002-9230-4137, Vencovsky, Jiri; https://orcid.org/0000-0002-0851-0713, Wang, Guochun, Wedderburn, Lucy R, Diederichsen, Louise Pyndt; https://orcid.org/0000-0002-2581-8912, Schmidt, Jens, Oakley, Paula, Benveniste, Olivier, Danieli, Maria Giovanna; https://orcid.org/0000-0002-9608-2252, Danko, Katalin, Thuy, Nguyen Thi Phuong, Vazquez-Del Mercado, Monica, Andersson, Helena, De Paepe, Boel, deBleecker, Jan L, Maurer, Britta, McCann, Liza J, Pipitone, Nicolo, McHugh, Neil, Betteridge, Zoe E, New, Paul, Cooper, Robert G, Ollier, William E, Lamb, Janine A, Krogh, Niels Steen, Lundberg, Ingrid E, and Chinoy, Hector

Published
2018

4. The EuroMyositis registry: an international collaborative tool to facilitate myositis research.

Author

Lilleker, James B., Vencovsky, Jiri, Wang, Guochun, Wedderburn, Lucy R., Diederichsen, Louise Pyndt, Schmidt, Jens, Oakley, Paula, Benveniste, Olivier, Danieli, Maria Giovanna, Danko, Katalin, Nguyen Thi Phuong Thuy, Mercado, Monica Vazquez-Del, Andersson, Helena, De Paepe, Boel, deBleecker, Jan L., Maurer, Britta, McCann, Liza J., Pipitone, Nicolo, McHugh, Neil, and Betteridge, Zoe E.

Subjects
COMPARATIVE studies, HEALTH status indicators, INTERNATIONAL relations, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, MEDICAL research, MYOSITIS, PROGNOSIS, QUESTIONNAIRES, RESEARCH, RESEARCH funding, SMOKING, EVALUATION research, ACQUISITION of data, CROSS-sectional method, SEVERITY of illness index
Abstract

Aims: The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data.Methods: Cross-sectional analysis of IIM cases from 11 countries was performed. Associations between clinical subtypes, extramuscular involvement, environmental exposures and medications were investigated.Results: Of 3067 IIM cases, 69% were female. The most common IIM subtype was dermatomyositis (DM) (31%). Smoking was more frequent in connective tissue disease overlap cases (45%, OR 1.44, 95% CI 1.09 to 1.90, p=0.012). Smoking was associated with interstitial lung disease (ILD) (OR 1.32, 95% CI 1.06 to 1.65, p=0.013), dysphagia (OR 1.43, 95% CI 1.16 to 1.77, p=0.001), malignancy ever (OR 1.78, 95% CI 1.36 to 2.33, p<0.001) and cardiac involvement (OR 2.40, 95% CI 1.60 to 3.60, p<0.001).Dysphagia occurred in 39% and cardiac involvement in 9%; either occurrence was associated with higher Health Assessment Questionnaire (HAQ) scores (adjusted OR 1.79, 95% CI 1.43 to 2.23, p<0.001). HAQ scores were also higher in inclusion body myositis cases (adjusted OR 3.85, 95% CI 2.52 to 5.90, p<0.001). Malignancy (ever) occurred in 13%, most commonly in DM (20%, OR 2.06, 95% CI 1.65 to 2.57, p<0.001).ILD occurred in 30%, most frequently in antisynthetase syndrome (71%, OR 10.7, 95% CI 8.6 to 13.4, p<0.001). Rash characteristics differed between adult-onset and juvenile-onset DM cases ('V' sign: 56% DM vs 16% juvenile-DM, OR 0.16, 95% CI 0.07 to 0.36, p<0.001). Glucocorticoids were used in 98% of cases, methotrexate in 71% and azathioprine in 51%.Conclusion: This large multicentre cohort demonstrates the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity. Our findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients. [ABSTRACT FROM AUTHOR]

Published
2018
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