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The article discusses ways on how to identify women at high risk of breast cancer. The link between supradiaphragmatic radiotherapy, which is being used for the treatment of Hodgkin's lymphoma, and breast cancer is tackled. Genes that increase the risk of the disease are cited, including mutations in BRCA1 and BRCA2 genes. It suggests approaches on how to obtain a family history of the condition. Information on bilateral risk reducing mastectomies and chemoprevention is presented.

The British Society of Gastroenterology (BSG) and the Association of Coloproctology for Great Britain and Ireland (ACPGBI) commissioned this update of the 2002 guidance. The aim, as before, is to provide guidance on the appropriateness, method and frequency of screening for people at moderate and high risk from colorectal cancer. This guidance provides some new recommendations for those with inflammatory bowel disease and for those at moderate risk resulting from a family history of colorectal cancer. In other areas guidance is relatively unchanged, but the recent literature was reviewed and is included where appropriate. [ABSTRACT FROM AUTHOR]