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2 results on '"Mann Chandavimol"'

1. Sex differences in patients undergoing transcatheter aortic valve replacement in Asia

Author

Yusuke Watanabe, Kentaro Hayashida, Mao Chen, Wei-Hsian Yin, Hsien-Li Kao, Mao-Shin Lin, Paul T L Chiam, Michael K Y Lee, Fabio Enrique Posas, Mann Chandavimol, Wacin Buddhari, Timothy C Dy, Ngoc Quang Nguyen, Won Jang Kim, Kiyuk Chang, Yat-Yin Lam, Hung Manh Pham, Shaiful Azmi Yahaya, Kay Woon Ho, Wenzhi Pan, Xian-bao Liu, Jian'an Wang, and Hyo Soo Kim

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Objectives Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.Methods Patients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.Results Eight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, p

Published
2021
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2. Sex differences in patients undergoing transcatheter aortic valve replacement in Asia

Author

Mann Chandavimol, Kiyuk Chang, Yat Yin Lam, Wei Hsian Yin, Wenzhi Pan, Mao-Shin Lin, Kentaro Hayashida, Hsien-Li Kao, Shaiful Azmi Yahaya, Yusuke Watanabe, Timothy C. Dy, Won Kim, Michael K.Y. Lee, Mao Chen, Fabio Enrique B. Posas, Jian-an Wang, Xian Bao Liu, Ngoc Quang Nguyen, Hung Manh Pham, Kay Woon Ho, Hyo-Soo Kim, Paul T.L. Chiam, and Wacin Buddhari

Subjects
Male, medicine.medical_specialty, Asia, Time Factors, Transcatheter aortic, medicine.medical_treatment, aortic valve stenosis, 030204 cardiovascular system & hematology, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Sex Factors, Valve replacement, Internal medicine, medicine, Humans, Diseases of the circulatory (Cardiovascular) system, In patient, 030212 general & internal medicine, Registries, Stroke, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Mortality rate, Incidence, medicine.disease, heart valve prosthesis implantation, medicine.anatomical_structure, Treatment Outcome, Aortic valve stenosis, Aortic Valve, Valvular Heart Disease, RC666-701, Female, Permanent pacemaker, Cardiology and Cardiovascular Medicine, business, Artery
Abstract

ObjectivesTranscatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller aortic root and peripheral vessel anatomy. The influence of gender of Asian patients undergoing TAVR is unknown and may affect outcomes. The aim of this study was to assess sex differences in Asian patients undergoing TAVR.MethodsPatients undergoing TAVR from eight countries were enrolled. In this retrospective analysis, we examined differences in characteristics, 30-day clinical outcomes and 1-year survival between female and male Asian patients.ResultsEight hundred and seventy-three patients (54.4% women) were included. Women were older, smaller and had less coronary artery and lung disease but tended to have higher logistic EuroSCOREs. Smaller prostheses were used more often in women. Major vascular complications occurred more frequently in women (5.5% vs 1.8%, pConclusionsAsian women had significantly smaller stature and anatomy with some differences in clinical profiles. Despite more frequent major vascular complications, women had similar 30-day stroke or mortality rates. Functional status improvement was significant and comparable between the sexes. Conduction disturbance and permanent pacemaker requirements were similar as was 1-year survival.

Published
2021

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