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Aim of special session Understand the role of biomarkers for early interventions in occupational health settings Work-related contact dermatitis represent a substantive part of occupational diseases in many countries of the World. They cause extensive suffering for the affected workers and represent a huge socio-economic burden. Selection of appropriate biomarkers, including those involved in skin barrier and inflammation, can provide the basis for early, health-protective interventions in occupational health settings. Furthermore, they allow identify new potential therapeutic targets, aid diagnostics and monitoring of therapy and interventions to improve workers’ skin health