1. Aspects of oxidative metabolism in schizophrenia.
- Author
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Marchbanks, A. M., Mulcrone, J., Whatley, S. A., and Marchbanks, R M
- Subjects
SCHIZOPHRENIA ,MOLECULAR biology ,MITOCHONDRIA ,CYTOCHROME oxidase ,DOPAMINERGIC mechanisms ,ESTROGEN ,METABOLISM ,MITOCHONDRIAL physiology ,NEURAL physiology ,DRUG therapy for schizophrenia ,ANTIPSYCHOTIC agents ,BRAIN ,ENERGY metabolism ,ENZYMES ,NEURONS ,PSYCHOLOGY ,PHYSIOLOGY - Abstract
The article discusses a study on the biological phenomenology of schizophrenia with the use of molecular analysis. The results indicate the involvement of altered mitochondrial function in the symptomatology and etiology of schizophrenia. The subunits of cytochrome oxidase are the mitochondrial components that are significant because of their expression to dopaminergic blockade and upregulation by estrogen.
- Published
- 1995
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