1. Viral respiratory infections diagnosed by multiplex PCR after allogeneic hematopoietic stem cell transplantation: long-term incidence and outcome.
- Author
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Wolfromm A, Porcher R, Legoff J, Peffault de Latour R, Xhaard A, de Fontbrune FS, Ribaud P, Bergeron A, Socié G, and Robin M
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Cohort Studies, Female, Hematopoietic Stem Cell Transplantation mortality, Humans, Incidence, Male, Middle Aged, Respiratory Tract Infections etiology, Respiratory Tract Infections virology, Transplantation Conditioning mortality, Transplantation, Homologous mortality, Treatment Outcome, Young Adult, Hematopoietic Stem Cell Transplantation adverse effects, Multiplex Polymerase Chain Reaction methods, Respiratory Tract Infections diagnosis, Transplantation Conditioning adverse effects, Transplantation, Homologous adverse effects
- Abstract
Viral respiratory infections (VRIs) are frequent after hematopoietic stem cell transplantation and constitute a potential cause of mortality. We analyzed the incidence, risk factors, and prognosis of VRIs in a cohort of transplanted patients. More frequent viruses were human coronavirus and human rhinovirus followed by flu-like viruses and adenovirus. Risk factors for death were lymphocytopenia and high steroid dosage., (Copyright © 2014 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.) more...
- Published
- 2014
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