1. Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.
- Author
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Wen-Yang Tsai, Han Ha Youn, Tyson, Jasmine, Brites, Carlos, Jih-Jin Tsai, Pedroso, Celia, Drexler, Jan Felix, Balmaseda, Angel, Harris, Eva, Wei-Kung Wang, Tsai, Wen-Yang, Youn, Han Ha, Tsai, Jih-Jin, and Wang, Wei-Kung
- Subjects
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SERODIAGNOSIS , *ZIKA virus , *ZIKA virus infections , *UREA , *DENGUE viruses , *VIRAL nonstructural proteins , *DISEASE complications , *DIAGNOSIS , *VIRAL transmission - Abstract
Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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