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Your search keyword '"Fabian H, Leendertz"' showing total 15 results
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15 results on '"Fabian H, Leendertz"'

1. Role of Wildlife in Emergence of Ebola Virus in Kaigbono (Likati), Democratic Republic of the Congo, 2017

Author

Sophie Gryseels, Placide Mbala-Kingebeni, Innocent Akonda, Roger Angoyo, Ahidjo Ayouba, Pascal Baelo, Daniel Bamuleka Mukadi, Elie Bugentho, Trenton Bushmaker, Christelle Butel, Sébastien Calvignac-Spencer, Eric Delaporte, Birgit De Smet, Ariane Düx, François Edidi-Atani, Robert Fischer, Corneille Kahandi, Jimmy Kapetshi, Servet Kimbonza Sumba, Léonce Kouadio, André Malekani Bendeke, Claude Mande, Guy Midingi Sepolo, Joseph Moudindo, Eitel Mpoudi Ngole, Prescott Musaba, Patrick Mutombo, Innocent Ndong Bass, Casimir Nebesse, Steve Ngoy, Simon-Pierre Ndimbo Kumogo, Stephanie N. Seifert, Jacques Tanzito, Dudu Akaibe, Nicaise Amundala, Kevin K. Ariën, Guy-Crispin Gembu, Fabian H. Leendertz, Herwig Leirs, Jean-Claude Mukinzi, Vincent Munster, Jean-Jacques Muyembe-Tamfum, Martine Peeters, Erik Verheyen, and Steve Ahuka-Mundeke

Subjects
Ebola virus, ecology, infectious disease reservoir, mammals, zoonoses, viruses, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

After the 2017 Ebola virus (EBOV) outbreak in Likati, a district in northern Democratic Republic of the Congo, we sampled small mammals from the location where the primary case-patient presumably acquired the infection. None tested positive for EBOV RNA or antibodies against EBOV, highlighting the ongoing challenge in detecting animal reservoirs for EBOV.

Published
2020
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2. Yaws Disease Caused by Treponema pallidum subspecies pertenue in Wild Chimpanzee, Guinea, 2019

Author

Benjamin Mubemba, Emeline Chanove, Kerstin Mätz-Rensing, Jan F. Gogarten, Ariane Düx, Kevin Merkel, Caroline Röthemeier, Andreas Sachse, Helene Rase, Tatyana Humle, Guillaume Banville, Marine Tchoubar, Sébastien Calvignac-Spencer, Christelle Colin, and Fabian H. Leendertz

Subjects
yaws disease, chimpanzee, Treponema pallidum, bacteria, Guinea, Treponema pallidum subspecies pertenue, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Yaws-like lesions are widely reported in wild African great apes, yet the causative agent has not been confirmed in affected animals. We describe yaws-like lesions in a wild chimpanzee in Guinea for which we demonstrate infection with Treponema pallidum subsp. pertenue. Assessing the conservation implications of this pathogen requires further research.

Published
2020
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3. No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana

Author

Sandra Junglen, Marco Marklewitz, Florian Zirkel, Robert Wollny, Benjamin Meyer, Hanna Heidemann, Sonja Metzger, Augustina Annan, Dickson Dei, Fabian H. Leendertz, Samuel Oppong, and Sung Sup Park

Subjects
viruses, arbovirus, bunyavirus, insects, Gouléako virus, Herbert virus, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

A recent report suggested that 2 novel bunyaviruses discovered in insects in Côte d’Ivoire caused lethal disease in swine in South Korea. We conducted cell culture studies and tested serum from pigs exposed to mosquitoes in Côte d’Ivoire and Ghana and found no evidence for infection in pigs.

Published
2015
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4. Lassa Virus in Multimammate Rats, Côte d’Ivoire, 2013

Author

Leonce Kouadio, Kathrin Nowak, Chantal Akoua-Koffi, Sabrina Weiss, Bernard K. Allali, Peter T. Witkowski, Detlev H. Krüger, Emmanuel Couacy-Hymann, Sébastien Calvignac-Spencer, and Fabian H. Leendertz

Subjects
Lassa fever, Lassa virus, viruses, zoonoses, multimammate rat, Côte d’Ivoire, Medicine, Infectious and parasitic diseases, RC109-216
Published
2015
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5. Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee

Author

Mireia Coscolla, Astrid Lewin, Sonja Metzger, Kerstin Maetz-Rennsing, Sébastien Calvignac-Spencer, Andreas Nitsche, Pjotr Wojtek Dabrowski, Aleksandar Radonic, Stefan Niemann, Julian Parkhill, Emmanuel Couacy-Hymann, Julia Feldman, Iñaki Comas, Christophe Boesch, Sebastien Gagneux, and Fabian H. Leendertz

Subjects
tuberculosis and other mycobacteria, bacteria, Mycobacterium tuberculosis, MTBC, wild chimpanzee, zoonoses, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Tuberculosis (TB) is caused by gram-positive bacteria known as the Mycobacterium tuberculosis complex (MTBC). MTBC include several human-associated lineages and several variants adapted to domestic and, more rarely, wild animal species. We report an M. tuberculosis strain isolated from a wild chimpanzee in Côte d’Ivoire that was shown by comparative genomic and phylogenomic analyses to belong to a new lineage of MTBC, closer to the human-associated lineage 6 (also known as M. africanum West Africa 2) than to the other classical animal-associated MTBC strains. These results show that the general view of the genetic diversity of MTBC is limited and support the possibility that other MTBC variants exist, particularly in wild mammals in Africa. Exploring this diversity is crucial to the understanding of the biology and evolutionary history of this widespread infectious disease.

Published
2013
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6. Origin of Human T-Lymphotropic Virus Type 1 in Rural Côte d’Ivoire

Author

Sébastien Calvignac-Spencer, Edgard V. Adjogoua, Chantal Akoua-Koffi, Claudia Hedemann, Grit Schubert, Heinz Ellerbrok, Siv Aina Jensen Leendertz, Georg Pauli, and Fabian H. Leendertz

Subjects
human T-lymphotropic virus type 1, HTLV-1, simian T-lymphotropic virus type 1, STLV-1, zoonosis, non-human primates, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Simian T-lymphotropic virus type 1 (STLV-1) strains occasionally infect humans. However, the frequency of such infections is unknown. We show that direct transmission of STLV-1 from nonhuman primates to humans may be responsible for a substantial proportion of human T-lymphotropic virus type 1 infections in rural Côte d’Ivoire, where primate hunting is common.

Published
2012
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7. Diversity of Parvovirus 4–like Viruses in Humans, Chimpanzees, and Monkeys in Hunter–Prey Relationships

Author

Cornelia Adlhoch, Marco Kaiser, Anna Loewa, Markus Ulrich, Christian Forbrig, Edgard V. Adjogoua, Chantal Akoua-Koffi, Emmanuel Couacy-Hymann, Siv Aina J. Leendertz, Wolfram Rietschel, Christophe Boesch, Heinz Ellerbrok, Bradley S. Schneider, and Fabian H. Leendertz

Subjects
chimpanzees, Côte d’Ivoire, colobus monkeys, partetetravirus, parvovirus 4, PARV4, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

During 2010–2011, we investigated interspecies transmission of partetraviruses between predators (humans and chimpanzees) and their prey (colobus monkeys) in Côte d’Ivoire. Despite widespread infection in all species investigated, no interspecies transmission could be detected by PCR and genome analysis. All sequences identified formed species- or subspecies (chimpanzee)-specific clusters, which supports a co-evolution hypothesis.

Published
2012
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8. Fatal Monkeypox in Wild-Living Sooty Mangabey, Côte d’Ivoire, 2012

Author

Aleksandar Radonić, Sonja Metzger, Piotr Wojtek Dabrowski, Emmanuel Couacy-Hymann, Livia Schuenadel, Andreas Kurth, Kerstin Mätz-Rensing, Christophe Boesch, Fabian H. Leendertz, and Andreas Nitsche

Subjects
Poxvirus, monkeypox virus, zoonoses, Taï National Park, viruses, Côte d’Ivoire, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

We isolated a monkeypox virus from a wild-living monkey, a sooty mangabey, found dead in Taï National Park, Côte d’Ivoire, in March 2012. The whole-genome sequence obtained from this isolate and directly from clinical specimens showed its close relationship to monkeypox viruses from Western Africa.

Published
2014
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9. Wild Chimpanzees Infected with 5 Plasmodium Species

Author

Marco Kaiser, Anna Löwa, Markus Ulrich, Heinz Ellerbrok, Adeelia S. Goffe, Anja Blasse, Zinta Zommers, Emmanuel Couacy-Hymann, Fred Babweteera, Klaus Zuberbühler, Sonja Metzger, Sebastian Geidel, Christophe Boesch, Thomas R. Gillespie, and Fabian H. Leendertz

Subjects
Wild chimpanzees, Plasmodium, zoonoses, human malaria, parasites, natural diversity, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Data are missing on the diversity of Plasmodium spp. infecting apes that live in their natural habitat, with limited possibility of human-mosquito-ape exchange. We surveyed Plasmodium spp. diversity in wild chimpanzees living in an undisturbed tropical rainforest habitat and found 5 species: P. malariae, P. vivax, P. ovale, P. reichenowi, and P. gaboni.

Published
2010
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10. Global Distribution of Novel Rhinovirus Genotype

Author

Thomas Briese, Neil Renwick, Marietjie Venter, Richard G. Jarman, Dhrubaa Ghosh, Sophie Köndgen, Sanjaya K. Shrestha, A. Mette Hoegh, Inmaculada Casas, Edgard Valerie Adjogoua, Chantal Akoua-Koffi, Khin Saw Myint, David T. Williams, Glenys R. Chidlow, Ria van den Berg, Cristina Calvo, Orienka Koch, Gustavo Palacios, Vishal Kapoor, Joseph Villari, Samuel R. Dominguez, Kathryn V. Holmes, Gerry Harnett, David W. Smith, John S. MacKenzie, Heinz Ellerbrok, Brunhilde Schweiger, Kristian Schønning, Mandeep S. Chadha, Fabian H. Leendertz, A.C. Mishra, Robert V. Gibbons, Edward C. Holmes, and W. Ian Lipkin

Subjects
picornavirus, rhinovirus, HRV-C, multiplex MassTag PCR, lower respiratory tract infection, childhood pneumonia, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Global surveillance for a novel rhinovirus genotype indicated its association with community outbreaks and pediatric respiratory disease in Africa, Asia, Australia, Europe, and North America. Molecular dating indicates that these viruses have been circulating for at least 250 years.

Published
2008
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11. Hantavirus in Bat, Sierra Leone

Author

Sabrina Weiss, Peter T. Witkowski, Brita Auste, Kathrin Nowak, Natalie Weber, Jakob Fahr, Jean-Vivien Mombouli, Nathan D. Wolfe, Ana Maria Bispo de Filippis, Sung Sup Park, Boris Klempa, Fabian H. Leendertz, and Detlev H. Kruger

Subjects
hantavirus, rodent-borne pathogens, bats, Africa, Chiroptera, Sierra Leone, Medicine, Infectious and parasitic diseases, RC109-216
Published
2012
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13. No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana

Author

Fabian H. Leendertz, Sonja Metzger, Sandra Junglen, Florian Zirkel, Hanna Heidemann, Robert Wollny, Dickson Dei, A. P. Annan, Samuel Oppong, Christian Drosten, Marco Marklewitz, and Benjamin Meyer

Subjects
Microbiology (medical), Veterinary medicine, Orthobunyavirus, Swine, Epidemiology, vector-borne infections, lcsh:Medicine, Cote d ivoire, Bunyaviridae Infections, bunyavirus, arthropods, Ghana, Arbovirus, Virus, lcsh:Infectious and parasitic diseases, No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana, Gouléako virus, South Korea, parasitic diseases, medicine, Animals, viruses, lcsh:RC109-216, insects, mosquitoes, biology, Côte d’Ivoire, fungi, lcsh:R, Dispatch, pigs, Herbert virus, medicine.disease, biology.organism_classification, Virology, Cote d'Ivoire, Culicidae, PCR, Infectious Diseases, arbovirus, Africa
Abstract

A recent report suggested that 2 novel bunyaviruses discovered in insects in Côte d’Ivoire caused lethal disease in swine in South Korea. We conducted cell culture studies and tested serum from pigs exposed to mosquitoes in Côte d’Ivoire and Ghana and found no evidence for infection in pigs.

Published
2015

14. Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee

Author

Julian Parkhill, Astrid Lewin, Sonja Metzger, Sebastien Gagneux, Julia Feldman, Andreas Nitsche, Kerstin Maetz-Rennsing, Pjotr Wojtek Dabrowski, Christophe Boesch, Fabian H. Leendertz, Emmanuel Couacy-Hymann, Mireia Coscolla, Iñaki Comas, Aleksandar Radonić, Stefan Niemann, and Sébastien Calvignac-Spencer

Subjects
Microbiology (medical), Tuberculosis, Pan troglodytes, Epidemiology, MTBC, lcsh:Medicine, nonhuman primate, Polymorphism, Single Nucleotide, lcsh:Infectious and parasitic diseases, West africa, Mycobacterium tuberculosis, 03 medical and health sciences, Phylogenetics, medicine, M. tuberculosis, Animals, lcsh:RC109-216, mammals, Animal species, bacteria, Phylogeny, 030304 developmental biology, Genetics, 0303 health sciences, Genetic diversity, biology, 030306 microbiology, Research, lcsh:R, Sequence Analysis, DNA, biology.organism_classification, medicine.disease, infection, 3. Good health, tuberculosis and other mycobacteria, zoonoses, Ape Diseases, Infectious Diseases, TB, Mycobacterium tuberculosis complex, tuberculosis, Infectious disease (medical specialty), wild chimpanzee, Africa, Female, Genome, Bacterial, lineage
Abstract

Tuberculosis (TB) is caused by gram-positive bacteria known as the Mycobacterium tuberculosis complex (MTBC). MTBC include several human-associated lineages and several variants adapted to domestic and, more rarely, wild animal species. We report an M. tuberculosis strain isolated from a wild chimpanzee in Côte d’Ivoire that was shown by comparative genomic and phylogenomic analyses to belong to a new lineage of MTBC, closer to the human-associated lineage 6 (also known as M. africanum West Africa 2) than to the other classical animal-associated MTBC strains. These results show that the general view of the genetic diversity of MTBC is limited and support the possibility that other MTBC variants exist, particularly in wild mammals in Africa. Exploring this diversity is crucial to the understanding of the biology and evolutionary history of this widespread infectious disease.

Published
2013

15. Wild Chimpanzees Infected with 5 Plasmodium Species

Author

Adeelia S. Goffe, Marco Kaiser, Markus Ulrich, Heinz Ellerbrok, Fred Babweteera, Fabian H. Leendertz, Klaus Zuberbühler, Thomas R. Gillespie, Anja Blasse, Emmanuel Couacy-Hymann, Zinta Zommers, Sebastian Geidel, Anna Löwa, Christophe Boesch, and Sonja Metzger

Subjects
Microbiology (medical), Disease reservoir, Plasmodium, Pan troglodytes, Epidemiology, viruses, Molecular Sequence Data, Protozoan Proteins, lcsh:Medicine, Rainforest, Biology, parasites, tropical rain forest, Laverania, Trees, lcsh:Infectious and parasitic diseases, stomatognathic system, parasitic diseases, medicine, Animals, lcsh:RC109-216, human malaria, Phylogeny, Disease Reservoirs, natural diversity, Molecular Epidemiology, Tropical Climate, Base Sequence, Ecology, lcsh:R, Dispatch, Genetic Variation, medicine.disease, biology.organism_classification, Malaria, zoonoses, Ape Diseases, Infectious Diseases, Cote d'Ivoire, Habitat, Epidemiological Monitoring, Wild chimpanzees, human activities, Tropical rainforest, Environmental Monitoring
Abstract

Data are missing on the diversity of Plasmodium spp. infecting apes that live in their natural habitat, with limited possibility of human-mosquito-ape exchange. We surveyed Plasmodium spp. diversity in wild chimpanzees living in an undisturbed tropical rainforest habitat and found 5 species: P. malariae, P. vivax, P. ovale, P. reichenowi, and P. gaboni.

Published
2010

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